ID G9KUP8_MUSPF Unreviewed; 492 AA.
AC G9KUP8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Thymocyte selection-associated high mobility group box {ECO:0000313|EMBL:AES08627.1};
DE Flags: Fragment;
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|EMBL:AES08627.1};
RN [1] {ECO:0000313|EMBL:AES08627.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lungs {ECO:0000313|EMBL:AES08627.1};
RX PubMed=23236062; DOI=10.1128/JVI.02476-12;
RA Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F.,
RA Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M.,
RA Farooqui A., Kelvin D.J.;
RT "Sequencing, annotation, and characterization of the influenza ferret
RT infectome.";
RL J. Virol. 87:1957-1966(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JP020029; AES08627.1; -; mRNA.
DR AlphaFoldDB; G9KUP8; -.
DR HOGENOM; CLU_030650_2_0_1; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21995; HMG-box_TOX-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45781; AGAP000281-PA; 1.
DR PANTHER; PTHR45781:SF4; THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX; 1.
DR Pfam; PF00505; HMG_box; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}.
FT DOMAIN 227..295
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 227..295
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AES08627.1"
FT NON_TER 492
FT /evidence="ECO:0000313|EMBL:AES08627.1"
SQ SEQUENCE 492 AA; 53698 MW; D013F1F21C998638 CRC64;
FDGENMYMSM TEPSQDYVPA SQSYPGPSLE SEDFNIPPIT PPSLPDHSLV HVNEVEPGYH
SLCHPMNHNG LLPFHPQNMD LPEITVSNLL GQDGALLTNS ISVMQDIRNP EGTQYGSHPQ
MAAMRPRGQP ADIRQQPGMM QHGQLTTINQ SQLSAQLGLN MGGSSVPHNS PSPPGSKSAT
PSPSSSVHED EGDDTAKING GEKRPASDMG KKPKTPKKKK KKDPNEPQKP VSAYALFFRD
TQAAIKGQNP NATFGEVSKI VASMWDGLGE EQKQVYKKKT EAAKKEYLKQ LAAYRASLVS
KSYSEPVDVK TSQPPQLINS KPSVFHGPSQ AHSALYLSSH YHQQPGMNPH LTAMHPSLPR
SIAPKPNNQM PVTVSIANMA VSPPPPLQIS PPLHQHLNMQ QHPPLAMQQP LGNQLPMQVQ
SALHSPPMQQ GFTLQPDYQT IINPTSTAAQ VVTQAMEYVR SGCRNPPAQP VDWNNDYCSS
GGMQRDKALY LT
//
