ID   G9P2E2_HYPAI            Unreviewed;       303 AA.
AC   G9P2E2;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=haloalkane dehalogenase {ECO:0000256|ARBA:ARBA00012065};
DE            EC=3.8.1.5 {ECO:0000256|ARBA:ARBA00012065};
GN   ORFNames=TRIATDRAFT_78855 {ECO:0000313|EMBL:EHK43615.1};
OS   Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma
OS   atroviride).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=452589 {ECO:0000313|EMBL:EHK43615.1, ECO:0000313|Proteomes:UP000005426};
RN   [1] {ECO:0000313|EMBL:EHK43615.1, ECO:0000313|Proteomes:UP000005426}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20476 / IMI 206040 {ECO:0000313|Proteomes:UP000005426};
RX   PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA   Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA   Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA   Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA   Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA   McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA   Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA   Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA   Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA   Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA   Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA   Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA   Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA   Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT   "Comparative genome sequence analysis underscores mycoparasitism as the
RT   ancestral life style of Trichoderma.";
RL   Genome Biol. 12:R40.1-R40.15(2011).
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   -!- SIMILARITY: Belongs to the haloalkane dehalogenase family. Type 2
CC       subfamily. {ECO:0000256|ARBA:ARBA00007213}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHK43615.1}.
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DR   EMBL; ABDG02000026; EHK43615.1; -; Genomic_DNA.
DR   RefSeq; XP_013941770.1; XM_014086295.1.
DR   AlphaFoldDB; G9P2E2; -.
DR   SMR; G9P2E2; -.
DR   STRING; 452589.G9P2E2; -.
DR   ESTHER; hypai-g9p2e2; Haloalkane_dehalogenase-HLD2.
DR   GeneID; 25785400; -.
DR   eggNOG; KOG4178; Eukaryota.
DR   HOGENOM; CLU_020336_13_3_1; -.
DR   OMA; NTWAWPL; -.
DR   OrthoDB; 4074061at2759; -.
DR   Proteomes; UP000005426; Unassembled WGS sequence.
DR   GO; GO:0018786; F:haloalkane dehalogenase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   HAMAP; MF_01231; Haloalk_dehal_type2; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR000639; Epox_hydrolase-like.
DR   InterPro; IPR023594; Haloalkane_dehalogenase_2.
DR   PANTHER; PTHR43329; EPOXIDE HYDROLASE; 1.
DR   PANTHER; PTHR43329:SF74; HALOALKANE DEHALOGENASE; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00412; EPOXHYDRLASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005426}.
FT   DOMAIN          39..285
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   303 AA;  35055 MW;  24CD6BA6F4663CC5 CRC64;
     MSTDRGLEIS AAFPYEKKKV RVLGNQMAYV DVGTTSESTV VFLHGNPTSS YLWRNVFPHV
     AKKSRCIIPD LIGFGDSDKV PELEYRVRDH QRYIDAFLDA VLPTERITLV IHDWGSALGF
     DWASRHEDRV AGIAFMEWIP ALGGGWDARP PQFRATFEPL RTPELGRKMI VEDNFFVETV
     LPRGVFRALT EEEMTEYRRP FLIPADREPT WRFPNEIPID GHPEEVWDKA QKYMKWLEGS
     DLPKLFFWVK PGAIIREEHF KTLSEKIKNV KTVYLGPGSH YVQEDYPHSI GQEVSEWMAE
     LKL
//