ID G9P9H0_HYPAI Unreviewed; 1308 AA.
AC G9P9H0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
GN ORFNames=TRIATDRAFT_252710 {ECO:0000313|EMBL:EHK40293.1};
OS Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma
OS atroviride).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=452589 {ECO:0000313|EMBL:EHK40293.1, ECO:0000313|Proteomes:UP000005426};
RN [1] {ECO:0000313|EMBL:EHK40293.1, ECO:0000313|Proteomes:UP000005426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20476 / IMI 206040 {ECO:0000313|Proteomes:UP000005426};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK40293.1}.
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DR EMBL; ABDG02000028; EHK40293.1; -; Genomic_DNA.
DR RefSeq; XP_013938452.1; XM_014082977.1.
DR STRING; 452589.G9P9H0; -.
DR GeneID; 25778699; -.
DR eggNOG; KOG0962; Eukaryota.
DR HOGENOM; CLU_006184_0_0_1; -.
DR OMA; FSDYYYR; -.
DR OrthoDB; 5477220at2759; -.
DR Proteomes; UP000005426; Unassembled WGS sequence.
DR GO; GO:0030870; C:Mre11 complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR004584; Rad50_eukaryotes.
DR NCBIfam; TIGR00606; rad50; 1.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005426};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..225
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT REGION 333..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 390..421
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 471..552
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 718..820
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 844..916
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 992..1075
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 333..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1308 AA; 150707 MW; 18E7F3609A542121 CRC64;
MSRIDKLSIS GVRSFSPAVR EAIQFNTPLT LIVGYNGSGK TTIIECLKYA TTGEQPPNSK
VGGAFIHDPK LAGEKEVLAQ VKLQFRSIND RQHVATRSMQ LTAKKNTRSL KTLDCSLVVV
NNGERTTTST RTAQLDEMIP ERLGVSRAVL DAVIFCHQDE SLWPLSEPSA LKKRFDEIFE
AQKYTKAIEN LKVLRKKQVE QLSMLQNDEA HNKANKDRGE RAEKRMSGLQ TEIESARDQC
EALTVEMQET QVRIKQKHEQ ANSFLQIVQN LSNKREQLEY RQDAINELKQ TIDELPETDD
ALERALSQYE ESMGRYQEEA EQNKAQYAEL QQELTNHRQS QSAKLAEQGK LQSDKEKYER
QLKARVQLVQ EAASQYNFRG FDEDVSDQHI QVFQDKIQKL LTEKRRELER LQKENAAELD
KATGVITELE GRKAARTQDR VSAKQRMGAI EKRTSVLQNE AGNIDVDEGA KAILDGQLDE
LESRFKHAQQ ELEKSNWDQQ LTEANDKQWQ LDNENEKLGR ELVECTRLAS ERAQLELRKK
EMSDRKRKLD TLIETWKPKL SNTLGDDWEP HTLESRFQSI QSRQSKAVQE AQKRRDQTRQ
KQQKVEYRLK TAKETHGKKT QEMNQMKQKV VAALQNVRDN AVVEDYVDEV AAVEQQVEEL
RTDLSLFDAL FDYYNKCKRM LDTQKKCRLC DRHFDDGQSA ALDRLSKKID KHLDPKGKVD
TEKDLKEAVD NLEALRAVRS AFDTYERLSA ELPALQDEWK TAENEFETLE KELEDEDALV
AAAEEKLRDL GDLSKTVANI SQTVREIKDA ETQVDRIVSQ QSSGGVTRSV EEIHELQSSI
SEQIRTLKNK ITKLTADRQR MKDQVNSLEL EKSELRNKIG RAAGQLEKKK DLQNQIQSLK
EDYTHQREVI QRTDEELEKL EPSITEARSA RDETLRHGRS KEQVITDERD AITSSIAEIK
KMDNDIQDYV DRGGMTNLSS NQRALASLDT AISTTEKEIA DLTVRTNKLK QDIDSGDRKR
KNFNDNLNYR KHLRTLDVLR KDIEDLEDRN AHEDYERLEA EARSLENTAN RLLAERGSVM
GTMKSKDEEL GRLLQEWDMD FKDAKHKYRE SHIRVETTKA AIQDLTQCGS AVDKAVMQYH
SMKMEDVNRI ASELWQTTYQ GTDIDTILIR SDNETANNKR NYNYRLCMVK QDTEMDMRGR
CSAGQKVLAS IIIRLALAES FGVNCGLIAL DEPTTNLDRD NIKSLAESLH RIIKTRQQQS
NFQLIVITHD EEFLRHMRCS DFCDSFFRVK RDEKQNSVIS RESITKIF
//
