ID G9VYU8_STRAT Unreviewed; 385 AA.
AC G9VYU8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Putative glycosyl transferase {ECO:0000313|EMBL:AEU17886.1};
GN Name=simB7 {ECO:0000313|EMBL:AEU17886.1};
OS Streptomyces antibioticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1890 {ECO:0000313|EMBL:AEU17886.1};
RN [1] {ECO:0000313|EMBL:AEU17886.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tue6040 {ECO:0000313|EMBL:AEU17886.1};
RX PubMed=11959542; DOI=10.1128/AAC.46.5.1174-1182.2002;
RA Trefzer A., Pelzer S., Schimana J., Stockert S., Bihlmaier C.,
RA Fiedler H.P., Welzel K., Vente A., Bechthold A.;
RT "Biosynthetic gene cluster of simocyclinone, a natural multihybrid
RT antibiotic.";
RL Antimicrob. Agents Chemother. 46:1174-1182(2002).
RN [2] {ECO:0000313|EMBL:AEU17886.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tue6040 {ECO:0000313|EMBL:AEU17886.1};
RA Trefzer A., Bechthold A.;
RT "The simocyclinone biosynthetic gene cluster isolated from Streptomyces
RT antibioticus Tue6040.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AF324838; AEU17886.1; -; Genomic_DNA.
DR AlphaFoldDB; G9VYU8; -.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProt.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR048284; EryCIII-like_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF21036; EryCIII-like_N; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:AEU17886.1}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..385
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003527687"
FT DOMAIN 23..220
FT /note="Erythromycin biosynthesis protein CIII-like N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21036"
FT DOMAIN 246..384
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
SQ SEQUENCE 385 AA; 40931 MW; 7C0779808020C4F1 CRC64;
MRILFVAAGS LATAFALAPV ATAARNAGHA VIMAGNDDVI PAITGVGLPG VSVSSLTIQD
FYTDRAGRPV EIPTVPQEQI LFTGRWFGRM AAAWLDPLRE LARAWKPDVV VGGTMSYAAG
LLAAELGVRY VRHAWDAIEA TGIDVGAVDV LEPELTRLGL DRLPVPELFI DVCPPSLLPP
EPHPAKHTLR MRWIPVNGQR QLEPWTYTRT ERPRVCLTTG SRVAHDAGEQ DLPRRSYEFL
CALSASFKDL DVDLVVATTD PAGKALEARV PGVRAGWVPL DVLARTCDVI VHHGGGTTSL
TAMAAAAPQV AVPQGAVPNL SAQRLAEYGA AISLFGSEGS PEVIVDACTK ILGDRSYAER
ARDLSHEIAG LALPSEAVDV VAELV
//
