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Database: UniProt
Entry: G9WF02_9LACT
LinkDB: G9WF02_9LACT
Original site: G9WF02_9LACT 
ID   G9WF02_9LACT            Unreviewed;       448 AA.
AC   G9WF02;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   05-JUL-2017, entry version 41.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=OKIT_0444 {ECO:0000313|EMBL:EHN58562.1};
OS   Oenococcus kitaharae DSM 17330.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Leuconostocaceae;
OC   Oenococcus.
OX   NCBI_TaxID=1045004 {ECO:0000313|EMBL:EHN58562.1, ECO:0000313|Proteomes:UP000004959};
RN   [1] {ECO:0000313|EMBL:EHN58562.1, ECO:0000313|Proteomes:UP000004959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17330 {ECO:0000313|EMBL:EHN58562.1};
RX   PubMed=22235313; DOI=10.1371/journal.pone.0029626;
RA   Borneman A.R., McCarthy J.M., Chambers P.J., Bartowsky E.J.;
RT   "Functional divergence in the genus oenococcus as predicted by genome
RT   sequencing of the newly-described species, Oenococcus kitaharae.";
RL   PLoS ONE 7:E29626-E29626(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EHN58562.1}.
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DR   EMBL; AFVZ01000001; EHN58562.1; -; Genomic_DNA.
DR   RefSeq; WP_007744923.1; NZ_KE386622.1.
DR   EnsemblBacteria; EHN58562; EHN58562; OKIT_0444.
DR   PATRIC; fig|1045004.4.peg.440; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000004959; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004959};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004959}.
FT   DOMAIN      144    275       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      354    423       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     152    159       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   448 AA;  50628 MW;  6152E4D2A70295F1 CRC64;
     MNDDYFDLNN FWKSVQDRFA DNMGETAYEN WIRPVRAASV DLANRTVSLQ VPSDLVMQAW
     DNGNYTAKFM EYAYDVAHDF FKPDLKVVKV VVNPVNNSNQ TSSNFQTNDY QLNPAFTFDT
     WVVGDANELA TSAAMAVSEQ PGRQYNPLLI YGSSGLGKTH LMEAIGNRLK EVQPNAIVRY
     ITTDDFMNDW VNAISKKSTS EFTDTYENVD LLLVDDIQML QGKDRFQEEF FNIFNKITKA
     QKQIVMTSDV LPKDIPGLNA RLVSRFMQGV AYDIQKPDFP TRLAILKNKS EEAGMQIDNQ
     TLTLIAEQID TNVRELEGAF NTLTLMARAG RPINVANAQK ILEHLNISRQ KVITVSDIQR
     IVAEDYGVGL SDLLGKKRNS DIVLPRQVAM YLIRTLTDTS LPKIGQAFGG RDHTTVMHGT
     EKIADLIETD YSMKQRIETL STKIKEKS
//
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