ID GLGA_RHIEC Reviewed; 480 AA.
AC Q2K485;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=RHE_CH03596;
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251;
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABC92351.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000133; ABC92351.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_042119019.1; NC_007761.1.
DR AlphaFoldDB; Q2K485; -.
DR SMR; Q2K485; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR KEGG; ret:RHE_CH03596; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_5; -.
DR OrthoDB; 9808590at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001936; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR NCBIfam; TIGR02095; glgA; 1.
DR PANTHER; PTHR45825; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR PANTHER; PTHR45825:SF11; STARCH SYNTHASE 1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..480
FT /note="Glycogen synthase"
FT /id="PRO_0000241796"
SQ SEQUENCE 480 AA; 52093 MW; 1A44F7C03ED3F117 CRC64;
MKVLSVSSEV FPLIKTGGLA DVSGALPIAL KAFGVETKTL LPGYPAVMKV IRDPVVRLEF
PDLLGERATV LEVDHEGLDL LVLDAPAYYD RPGGPYLDPL GKDYPDNWRR FAALSLAASE
IGAGLLPGWR PDLVHTHDWQ AALTSVYMRY YPTPELPSVL TIHNIAFQGQ FGSEIFPGLR
LPDHAFAIDG VEYYGTTGFL KGGLQTAHAI TTVSPTYADE ILTPEFGMGL EGVIATRIDD
LHGIVNGIDT DVWNPATDPV VHTHYGPTTL KNREENRRSI AEFFHLDNDD APIFCVISRL
TWQKGMDIVA NVADRIVAMG GKLVVLGSGE AALEGALLAS ASRNPGRIGV SIGYNEPMSH
LMQAGCDAII IPSRFEPCGL TQLYALRYGC VPIVARTGGL NDTVIDANHA ALAAKVATGI
QFSPVTETGM LQAIRRAMHF YADRKLWTQL QKQGMKSDVS WEKSAERYAA LYSSLVSKGM
//
