ID H0C0W8_9BURK Unreviewed; 548 AA.
AC H0C0W8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:EHL21623.1};
GN ORFNames=KYG_16567 {ECO:0000313|EMBL:EHL21623.1};
OS Acidovorax sp. NO-1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=512030 {ECO:0000313|EMBL:EHL21623.1, ECO:0000313|Proteomes:UP000003485};
RN [1] {ECO:0000313|EMBL:EHL21623.1, ECO:0000313|Proteomes:UP000003485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NO-1 {ECO:0000313|EMBL:EHL21623.1,
RC ECO:0000313|Proteomes:UP000003485};
RX PubMed=22374962; DOI=10.1128/JB.06814-11;
RA Huang Y., Li H., Rensing C., Zhao K., Johnstone L., Wang G.;
RT "Genome Sequence of the Facultative Anaerobic Arsenite-Oxidizing and
RT Nitrate-Reducing Bacterium Acidovorax sp. Strain NO1.";
RL J. Bacteriol. 194:1635-1636(2012).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; AGTS01000100; EHL21623.1; -; Genomic_DNA.
DR RefSeq; WP_008905970.1; NZ_AGTS01000100.1.
DR AlphaFoldDB; H0C0W8; -.
DR STRING; 512030.KYG_16567; -.
DR PATRIC; fig|512030.4.peg.3264; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000003485; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd12118; ttLC_FACS_AEE21_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF4; BUTANOATE--COA LIGASE AAE1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EHL21623.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003485}.
FT DOMAIN 26..406
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 456..530
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 548 AA; 59172 MW; 13BC1A0128BFD70E CRC64;
MTSIFDQHLP RNEANFAALS PLSFIERTAE VYPDRLAIVH GELRQTWAQT YARCRQLASA
LTKAGIGKND TVAVMLPNTP PMVEAHFGVP MAGAVLNTLN TRLDPEAIAF MLDHGEAKAV
IVDPEFSGTL AKALALRTAP TPLRVIEVQD ALYGPAVQSL GGTDYDAFVA SGDAAFAWSL
PADEWDAIAL NYTSGTTGNP KGVVYHHRGA ATNAISNVLE WDMPKHAVYL WTLPMFHCNG
WCFPWTIAAR AGVNVCLRRV DAQAIFDAIR NHGVTHYCGA PIVHGLLVNA PDAMKAGIPA
GVKAMVAGAA PPASMIEGME KMGFDLTHVY GLTEVYGPAT VCAKHEAWDG LDIGERARLN
ARQGVRYHLE RDVRVLDPET MLPVPQDGET MGEIMFKGNI AMKGYLKNPK ATEEAFAGGW
FHSGDLAVQY PDGYIKIKDR SKDIIISGGE NISSIEVEDV LYRHPDVLAA AVVAKPDAKW
GETPCAFVEL KAGAQTTPED IVAHCKKHLA GFKVPRAVVF GELPKTSTGK IQKFELRKQA
GSAAAIDL
//
