ID H0EFP5_GLAL7 Unreviewed; 902 AA.
AC H0EFP5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=M7I_1178 {ECO:0000313|EMBL:EHL02666.1};
OS Glarea lozoyensis (strain ATCC 74030 / MF5533).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1104152 {ECO:0000313|EMBL:EHL02666.1, ECO:0000313|Proteomes:UP000005446};
RN [1] {ECO:0000313|EMBL:EHL02666.1, ECO:0000313|Proteomes:UP000005446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 74030 / MF5533 {ECO:0000313|Proteomes:UP000005446};
RX PubMed=22302591; DOI=10.1128/EC.05302-11;
RA Youssar L., Gruening B.A., Erxleben A., Guenther S., Huettel W.;
RT "Genome sequence of the fungus Glarea lozoyensis: the first genome sequence
RT of a species from the Helotiaceae family.";
RL Eukaryot. Cell 11:250-250(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHL02666.1}.
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DR EMBL; AGUE01000020; EHL02666.1; -; Genomic_DNA.
DR AlphaFoldDB; H0EFP5; -.
DR HOGENOM; CLU_001366_2_0_1; -.
DR InParanoid; H0EFP5; -.
DR Proteomes; UP000005446; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 2.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000005446};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ SEQUENCE 902 AA; 102428 MW; BA4E4E79E9A68297 CRC64;
MEVHVRNVPI QSNDKSLRNC LKPWFAKLSI QDVDCQKGQG KPFASLTFLS IDDGQKFLAR
HGQVKALGPK HKHDLARFNK EPIRLASTSV AVGSWDVEEN EVVFSPQITW NVRGTAVFGQ
RVMMLTLDSG IRLDFRYAST LEVTTQDGND PAVTFTMWEV PRFFEKVVDD PIEELIARLG
LGQRPPPSPP RDGLRRKGPD RFRLPFIDQQ HESIAGCCLV YRIALERYQY TQSYMVVELG
GLMESLKHTS GMPVVLHQTT RVACSPKVYA KGLTELRGWL ASPNCPDVAE KEMKESPPQL
FAYMDLNPKV TIVFCEGIHI ITAISCAYSF VMKMGNPFGS ILAYPMKEYY KGDSRKFLRV
ESRSQSAVIL SSAIRILLLE HNPIDLRHVQ EIPDVERNGR TFSDGVGTSA KGMISLDSRL
KGNVLVVRDS MIKFRGSKSA DLEICEAAYR PLPMYLNRQL IKILEDMGVE DDYFLNLQAR
EVESLRAAAD NPMSASKFLT KQSIGETVHL PWLIIELAML NLDFVHDEFL KDTVDQKGAR
DLPSKLSGGD LDGDRYYIMW DELARPKRTF AAADYPKVSP VNIGRRVERE DMSDFFLQFM
ESDQLGRIAV NHRVKADQRP GGTNDPECLL MAEMHSTAVD FSKTGIPVDM SRMPFGNKYR
PDFEAPGPHV HIEEDGINFD DPTFEDPMEI EDEDDEYSTY RYYKSEKILG KLYRAIDERE
IFAKIQARVE AEGSARRSRI IDKVWEYVQK RVVGIQWEYL LDQASDIRDM YEDCLRDTMV
EYSSHPSRPL SELEAFTGNI LGKTGIQNKY QRERSKTMKE KFDLDATWII NCIIKDGDKP
SDEALAMSIA CFAVSLEDTN PYLGKMPLSS FKYVAAAVCL REVANLPGWS ELPKLDIFNT
AR
//
