ID   H0GVY6_SACCK            Unreviewed;      1100 AA.
AC   H0GVY6;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Ysp1p {ECO:0000313|EMBL:EHN02035.1};
GN   ORFNames=VIN7_7615 {ECO:0000313|EMBL:EHN02035.1};
OS   Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7)
OS   (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=1095631 {ECO:0000313|EMBL:EHN02035.1, ECO:0000313|Proteomes:UP000009009};
RN   [1] {ECO:0000313|EMBL:EHN02035.1, ECO:0000313|Proteomes:UP000009009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VIN7 {ECO:0000313|EMBL:EHN02035.1,
RC   ECO:0000313|Proteomes:UP000009009};
RX   PubMed=22136070; DOI=10.1111/j.1567-1364.2011.00773.x;
RA   Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H.,
RA   Pretorius I.S., Egholm M., Chambers P.J.;
RT   "The genome sequence of the wine yeast VIN7 reveals an allotriploid hybrid
RT   genome with Saccharomyces cerevisiae and Saccharomyces kudriavzevii
RT   origins.";
RL   FEMS Yeast Res. 12:88-96(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHN02035.1}.
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DR   EMBL; AGVY01000245; EHN02035.1; -; Genomic_DNA.
DR   AlphaFoldDB; H0GVY6; -.
DR   HOGENOM; CLU_001720_0_0_1; -.
DR   PhylomeDB; H0GVY6; -.
DR   Proteomes; UP000009009; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd13280; PH_SIP3; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR042067; Sip3_PH.
DR   InterPro; IPR031968; VASt.
DR   PANTHER; PTHR14248; CYCLIN Y, ISOFORM A; 1.
DR   PANTHER; PTHR14248:SF18; CYCLIN Y, ISOFORM A; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS51778; VAST; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        903..924
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        936..955
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          180..293
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          645..850
FT                   /note="VASt"
FT                   /evidence="ECO:0000259|PROSITE:PS51778"
SQ   SEQUENCE   1100 AA;  128263 MW;  A5AFD04FC9E1611E CRC64;
     MPLLPILIRE KLLNIIREST IHLCQIFLAT ANDINILTPQ NLQNETFKLF DIKHKYTEAS
     LDLTEAISLM KVNLDKFLVE TIDIVRKNNV ITTKNTKDLI DITPELTETL KDWSDWIESN
     LQTLQGLSSK LSEAKYAILK LSLARSKPSH LLQDYDLRNI RNLKFSLPNS ISDRNLSADK
     KGISGWLYMR TTVGHDPKRV VWVRRWCFLQ NSIFGLFSLS PSKTYVEETD KFGILWITVE
     YLPNESRNFC FRLKIQSPKC ETEEEGTHVD IILQAENIGD LKAWINMLNF HKRYALSIKD
     ENDPRYQLAT RKIEPQFFEF ASSSSTSTDK LLTSFSGKTL TLVEELKRKY ISEDDIYSII
     DNEAYHLKVI STPVATQLTH LALFSTFLSV SNYFPCATQA NTWGTANWND LSYLFNPLEG
     NAILESPKVL SASRFSVSYP DYYPYSLKVD DIQFRSIFFS VNHHFLQIPK ELVLLRYSSV
     WCPNNKQKFS SVAFVTLNHI YVYLNISGFS YLKRIDLLDI DSIEYDRSPK NASSRMLHMQ
     RGDGIKFNMS VFFTDRRAVA SKLQFLIENK AMHVPKGEKE VLEIFHGLDE EIEKEKKFIK
     DNLSQTELHS KDHNQLLKCT YDRHFENTKE TPLELMSRKV RLEKEARFYF QDSFKVGSKI
     LFHVLFGDKS QVFPSSLFLC KKGSNLNTNS YWERIRYAKQ DDSCQFELAR KLQFGLNRTS
     NFIKDQIWLK DDNDNCKIIL EQRAVKIKQN YYYEVDEGPI IVKFPLCHPL LICVKFIIAE
     RITSQGESLK KCDLAILYKF KYIESSGKMD TKVEKLWLLE NIHLNWILRY CKVEHLAISK
     KAREYLKKFN DREKMSNVIK LCGFLGVLPK EIVENDKKAG DFMQPVYINY DYLSLLKIFI
     KLIVFYLSSV VIRTAKILLA LLMIVWKCFT KVNRSLYYGL LVASLINLFF VGKSIRSYFS
     VKSAEALFQN YANADQSGLQ IMHRSLTLPD LDLLTKNMLD NDQVNPVLKR FDGEKNAYQY
     KETRQEIAIK RNQVLMELKI LQNTENELVQ GSYRKFLITE RDKCLTTQNE ISDLWVNDTK
     LQDYCMECFS EYDRLSAIPT
//