GenomeNet

Database: UniProt
Entry: H0HJU1_9RHIZ
LinkDB: H0HJU1_9RHIZ
Original site: H0HJU1_9RHIZ 
ID   H0HJU1_9RHIZ            Unreviewed;       486 AA.
AC   H0HJU1;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-SEP-2017, entry version 37.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=MAXJ12_01981 {ECO:0000313|EMBL:EHK59004.1};
OS   Mesorhizobium alhagi CCNWXJ12-2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=1107882 {ECO:0000313|EMBL:EHK59004.1, ECO:0000313|Proteomes:UP000003250};
RN   [1] {ECO:0000313|EMBL:EHK59004.1, ECO:0000313|Proteomes:UP000003250}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCNWXJ12-2 {ECO:0000313|EMBL:EHK59004.1,
RC   ECO:0000313|Proteomes:UP000003250};
RX   PubMed=22328758; DOI=10.1128/JB.06635-11;
RA   Zhou M., Chen W., Chen H., Wei G.;
RT   "Draft Genome Sequence of Mesorhizobium alhagi CCNWXJ12-2T, a Novel
RT   Salt-Resistant Species Isolated from the Desert of Northwestern
RT   China.";
RL   J. Bacteriol. 194:1261-1262(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AHAM01000021; EHK59004.1; -; Genomic_DNA.
DR   EnsemblBacteria; EHK59004; EHK59004; MAXJ12_01981.
DR   PATRIC; fig|1107882.3.peg.394; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000003250; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003250};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003250}.
FT   DOMAIN      177    304       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     185    192       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   486 AA;  54050 MW;  94CB654036DB7012 CRC64;
     MAASGSAEKA FDKVKAQLKA RLGGEVYSSW FGRMKVTEAS KGLVRISVPT AFLRSWINSH
     YLDLISELWK QEDPDVLKID IVVRTATRMA APAGEAEPAF ARKATRQVHT ALSAGTAAAA
     AVERATPARA NGADVEFRQS VLGSPLDPRY TFQSFIEGPS NRVALAASRA VAESNSRFNP
     LFLHATVGLG KTHLLQAIAA ESLKQNPKSR VVYLTAEYFM WRFATAIRDN NALTLKEQLR
     DIDLLIIDDM QFLQGKSIQH EFCHLINMLL DSAKQVVVAA DRPPSELESL EPRVRSRLNG
     GVALEMSAPD FGMRLGMLQL RLASAKADDH ALDISEEILT HVARTVTGSG RELEGAFNQL
     LFRQSFEPQI TIDRIDEILG HIYRSGEPKR VRIEDIQRIV ARHYNVSKTE LLSNRRTRTI
     VKPRQIAMYL AKVMTPRSLP EIGRRFGGRD HTTVLHAVRK IEDLSGGDNT LAQELELLRR
     LISDQA
//
DBGET integrated database retrieval system