ID   H0R6H7_9ACTN            Unreviewed;       447 AA.
AC   H0R6H7;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   SubName: Full=Diaminopimelate decarboxylase {ECO:0000313|EMBL:GAB20678.1};
GN   Name=lysA {ECO:0000313|EMBL:GAB20678.1};
GN   ORFNames=GOEFS_124_00100 {ECO:0000313|EMBL:GAB20678.1};
OS   Gordonia effusa NBRC 100432.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1077974 {ECO:0000313|EMBL:GAB20678.1, ECO:0000313|Proteomes:UP000035034};
RN   [1] {ECO:0000313|EMBL:GAB20678.1, ECO:0000313|Proteomes:UP000035034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 100432 {ECO:0000313|EMBL:GAB20678.1,
RC   ECO:0000313|Proteomes:UP000035034};
RA   Yoshida I., Takarada H., Hosoyama A., Tsuchikane K., Katsumata H.,
RA   Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia effusa NBRC 100432.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR600183-50};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAB20678.1}.
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DR   EMBL; BAEH01000124; GAB20678.1; -; Genomic_DNA.
DR   AlphaFoldDB; H0R6H7; -.
DR   STRING; 1077974.GOEFS_124_00100; -.
DR   eggNOG; COG0019; Bacteria.
DR   Proteomes; UP000035034; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR022644; De-COase2_N.
DR   InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43727:SF2; DIAMINOPIMELATE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED; 1.
DR   Pfam; PF02784; Orn_Arg_deC_N; 1.
DR   PRINTS; PR01179; ODADCRBXLASE.
DR   SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035034}.
FT   DOMAIN          57..246
FT                   /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02784"
FT   ACT_SITE        383
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT   MOD_RES         66
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ   SEQUENCE   447 AA;  48371 MW;  3E30BC26061628E4 CRC64;
     MVVTLPAVER DWARAARESS TLFDIARAVD GPFHVVHPPT FADNLDRITS ALAAENIDGM
     VYFGKKANKA AAWLTQCARP ATGVDVASVP ELVAALGGGI RGTDIGVTGA AKSDALLWLA
     MRHDCLIAID EYSELVRLAD LAVRTKLTPR VLLRIRPPAA PASRFGFGPD ELGDVVAKCA
     DLRIDLCGFS FHLDGYDPVP RAELAAELVD RCLRARSLGH RADRISIGGG IACAYVDETD
     WATFEEGRTD AWFHAGRNPQ RTYPYYQAPT GADMVTAIAR HESAGISLAE RLRDAGVALL
     IEPGRALVDG AGFSVFPVLG CKQSPTAGDI PEHLITTVAG LSMSVSEQWK GSEFLPDPIL
     VTPSDPRGRD DGPVYTAVGG SSCMEYDVLT WRLVQLPTTP RYGDLLVYPN TAGYQMDKNE
     SEFHQLPLPP KVIWADTSWR FDEGSRP
//