ID H0TA23_9BRAD Unreviewed; 643 AA.
AC H0TA23;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Membrane fusion protein (MFP) family protein {ECO:0000256|RuleBase:RU365093};
GN ORFNames=BRAS3809_7190007 {ECO:0000313|EMBL:CCE03300.1};
OS Bradyrhizobium sp. STM 3809.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=551936 {ECO:0000313|EMBL:CCE03300.1, ECO:0000313|Proteomes:UP000004098};
RN [1] {ECO:0000313|Proteomes:UP000004098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=STM 3809 {ECO:0000313|Proteomes:UP000004098};
RX PubMed=24704842; DOI=10.3390/genes3010035;
RA Mornico D., Miche L., Bena G., Nouwen N., Vermeglio A., Vallenet D.,
RA Smith A.A., Giraud E., Medigue C., Moulin L.;
RT "Comparative genomics of aeschynomene symbionts: insights into the
RT ecological lifestyle of nod-independent photosynthetic bradyrhizobia.";
RL Genes (Basel) 3:35-61(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU365093}; Single-pass membrane protein
CC {ECO:0000256|RuleBase:RU365093}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|RuleBase:RU365093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE03300.1}.
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DR EMBL; CAFJ01000689; CCE03300.1; -; Genomic_DNA.
DR RefSeq; WP_008965844.1; NZ_CAFJ01000689.1.
DR AlphaFoldDB; H0TA23; -.
DR OrthoDB; 9810980at2; -.
DR Proteomes; UP000004098; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006144; Secretion_HlyD_CS.
DR InterPro; IPR010129; T1SS_HlyD.
DR NCBIfam; TIGR01843; type_I_hlyD; 1.
DR PANTHER; PTHR30386:SF17; ALKALINE PROTEASE SECRETION PROTEIN APRE; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR PROSITE; PS00543; HLYD_FAMILY; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU365093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU365093}; Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:CCE03300.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000313|EMBL:CCE03300.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365093}.
FT DOMAIN 266..311
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 297..324
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 368..395
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..80
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 643 AA; 70486 MW; B7377C590AAEA39A CRC64;
MKHINDFRPF DDDGYVRPKT RAVGPQGDAL ILELQRLQGA FDDGSDDDPR ARRGSRDGGK
KRRRPPPAQT RVKPRKKKGS TMGRALSLFG LGAQAQRERR GEGIREMDWQ SPAPVRGREP
ELTPPPRHAP GRVPNNNMAV LDVREARRDG GFGDAPRLGP QNLPARLGQA PAVPQTGVRR
LVGTAGTALT TGMTFIAAQG TAADLDDDSD EQLVPRVGRM FENELRLGLR VLLVAAVFGG
GWLTLVPLAG AVVVPGNLVV QSNVKAIQHP TGGIIAEIKV DNGKRVAAGD LLVRLDATQS
QAQLQSITKQ LNEQRAKIAR LSAERDGLEQ PEYPATLTSR ADDPNIRAVI ASENALFKAR
AVTRKSQKEL LQGRIVQLNN EISGMEAQLD SKTKQIDLIK GELAGVQDLY DKRLVPLTRL
TTLQREAARI DGERGQLVSS VAETRSKISE AELQTVKIDQ DFRSEVVKDL SDSQAKEGDL
VEKSVAARDQ LDRIEMRAPN SGTIHQLAVH TIGGVIKPGE TVMELVPDSD ELQVEGHVQP
KDIDHVHTGQ DAMVHFNAFN SHTTPKLSGQ VSFVSPDITN DQRTGSTFYT VRITLPDEER
KRLGDVNLKP GMQAEVYVQT GSRTMLSYLM KPVLDQWRRA FVE
//
