ID H0V7F8_CAVPO Unreviewed; 354 AA.
AC H0V7F8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 7 {ECO:0000313|Ensembl:ENSCPOP00000005666.3};
GN Name=PPP1R7 {ECO:0000313|Ensembl:ENSCPOP00000005666.3};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000005666.3, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000005666.3}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000005666.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02019251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003474608.2; XM_003474560.3.
DR AlphaFoldDB; H0V7F8; -.
DR STRING; 10141.ENSCPOP00000005666; -.
DR Ensembl; ENSCPOT00000006350.3; ENSCPOP00000005666.3; ENSCPOG00000006285.4.
DR GeneID; 100725048; -.
DR KEGG; cpoc:100725048; -.
DR CTD; 5510; -.
DR VEuPathDB; HostDB:ENSCPOG00000006285; -.
DR eggNOG; KOG0531; Eukaryota.
DR GeneTree; ENSGT00940000158551; -.
DR HOGENOM; CLU_044236_1_1_1; -.
DR InParanoid; H0V7F8; -.
DR OMA; EVWASYN; -.
DR OrthoDB; 8274at2759; -.
DR TreeFam; TF105538; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000006285; Expressed in frontal cortex and 13 other cell types or tissues.
DR GO; GO:0005694; C:chromosome; IEA:Ensembl.
DR GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF12799; LRR_4; 3.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 10.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00446; LRRcap; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 9.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 330..348
FT /note="U2A'/phosphoprotein 32 family A C-terminal"
FT /evidence="ECO:0000259|SMART:SM00446"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 40776 MW; 2E8C5A0B5C6BCD6F CRC64;
MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHIGGIV ADLSEQSLKD GVEQEEHELA
VDMETICLDR DAEDVDLNHY RIGKIEGFEV LKKVKTLCLR QNLIKCIENL EELQSLRELD
LYDNQIKKIE NLEALTELEI LDISFNLLRN IEGIDKLTQL KKLFLVNNKI SKIENLSNLH
QLQMLELGSN RIRAIENIDT LTNLQSLFLG KNKITKLQNL DALTNLTVLS MQSNRLTKIE
GLQSLVNLRE LYLSHNGIEV IEGLENNNKL TMLDIASNRI KKIENISHLT ELQEFWMNDN
LLESWSDLDE LKGARSLETV YLEHNPLQRD PQYRRKVMLA LPSVRQIDAT FVRF
//
