ID H0VI27_CAVPO Unreviewed; 264 AA.
AC H0VI27;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Copper homeostasis protein cutC homolog {ECO:0000256|ARBA:ARBA00019014};
GN Name=CUTC {ECO:0000313|Ensembl:ENSCPOP00000009832.3};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000009832.3, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000009832.3}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000009832.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CutC family.
CC {ECO:0000256|ARBA:ARBA00007768}.
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DR EMBL; AAKN02002796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02002797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02002798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02002799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0VI27; -.
DR STRING; 10141.ENSCPOP00000009832; -.
DR Ensembl; ENSCPOT00000011042.3; ENSCPOP00000009832.3; ENSCPOG00000010941.4.
DR VEuPathDB; HostDB:ENSCPOG00000010941; -.
DR eggNOG; KOG4013; Eukaryota.
DR GeneTree; ENSGT00390000008454; -.
DR HOGENOM; CLU_050555_3_2_1; -.
DR InParanoid; H0VI27; -.
DR OMA; FHRAFDQ; -.
DR TreeFam; TF105937; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000010941; Expressed in heart and 13 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR Gene3D; 3.20.20.380; Copper homeostasis (CutC) domain; 1.
DR HAMAP; MF_00795; CutC; 1.
DR InterPro; IPR005627; CutC-like.
DR InterPro; IPR036822; CutC-like_dom_sf.
DR PANTHER; PTHR12598; COPPER HOMEOSTASIS PROTEIN CUTC; 1.
DR PANTHER; PTHR12598:SF0; COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG; 1.
DR Pfam; PF03932; CutC; 1.
DR SUPFAM; SSF110395; CutC-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
SQ SEQUENCE 264 AA; 28401 MW; 3002A8CF88FC0B86 CRC64;
MKRQGTSLER KLARIQSGTA GAPNGFLMEV CVDSVGAGRI ELCSGLLEGG TTPSMGVLQV
VKQSVQIPVF VMIRPRGGDF LYSDREIEVM KADIQLAKLY GADGLVFGAL TEDGYIDKEL
CMSLVALCRP LPVTFHRAFD MVHDPMAALE TLVTLGFERV LTSGCDSSAL EGLPLIKRLI
DQAKGRIVIM PGGGITDRNL QRILEGSGAT EFHCSARSSR DSGMKFRNSS VAMGASLSNS
EYTLKVTDVT KVRTLNAIAK NILV
//
