ID H0WDZ9_CAVPO Unreviewed; 510 AA.
AC H0WDZ9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Ubiquilin 1 {ECO:0008006|Google:ProtNLM};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000021223.2, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000021223.2}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000021223.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAKN02046568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WDZ9; -.
DR STRING; 10141.ENSCPOP00000021223; -.
DR Ensembl; ENSCPOT00000024370.2; ENSCPOP00000021223.2; ENSCPOG00000021805.2.
DR VEuPathDB; HostDB:ENSCPOG00000021805; -.
DR eggNOG; KOG0010; Eukaryota.
DR GeneTree; ENSGT00940000163907; -.
DR HOGENOM; CLU_024293_4_0_1; -.
DR InParanoid; H0WDZ9; -.
DR OMA; VKTPQDC; -.
DR TreeFam; TF314412; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000021805; Expressed in testis.
DR CDD; cd14399; UBA_PLICs; 1.
DR CDD; cd01808; Ubl_PLICs; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR015496; Ubiquilin.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10677; UBIQUILIN; 1.
DR PANTHER; PTHR10677:SF10; UBIQUILIN 5; 1.
DR Pfam; PF00240; ubiquitin; 1.
DR SMART; SM00165; UBA; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT DOMAIN 24..96
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 466..507
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 255..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 56066 MW; 6E0882E91734FF36 CRC64;
MAQPREEAGD NQLVSGQEPS SCIIRVSVKT PQDCQEFLIS ENSTVRHFKK QISKRFHCDT
DRLVLIFTGK ILRDQDILGQ RCIHDGDTVH LVVRSRLKGL VSPITLPNAT DHCTHRSEPS
ARLGRLARTS PELADFFGQL AQLLTTAPEC VVHFLEDPLI QGLASEKQTI ASHIPEPSRP
AQKHDSTLKT LETLQKPARQ QELLEASKQK LEALKAVPGG DNAMRPVSSD VQQFMLSTLA
LLITSKDYNS GSEACRGEAN VHSSSDTTTT IPTTSAPARP LVPEVSVGAF TQGRGVALNQ
ASSGCKNGMP VLYLGQDLPS QDTQQPVEKA YLTNQLRPLP SLLCQALHVL QQNPTVLRQL
SNSPLRRHIP LLLPILTNPR ALQALIQIEQ GLQILFREVP GLRPFLQDSA RLHGARRVPE
SRGRRQGHRE DPMQPTLAVL QLLHALANAC SLSTQLPLFS SLLTESRYQQ ELEQLKALGF
ANRNANLQAL ITTNGDIPAA IEKLLEEPQA
//
