ID H0WTE8_OTOGA Unreviewed; 355 AA.
AC H0WTE8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Solute carrier family 25 member 14 {ECO:0000313|Ensembl:ENSOGAP00000005424.2};
GN Name=SLC25A14 {ECO:0000313|Ensembl:ENSOGAP00000005424.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005424.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000005424.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; AAQR03131097; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131098; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131100; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WTE8; -.
DR STRING; 30611.ENSOGAP00000005424; -.
DR Ensembl; ENSOGAT00000006069.2; ENSOGAP00000005424.2; ENSOGAG00000006069.2.
DR eggNOG; KOG0753; Eukaryota.
DR GeneTree; ENSGT00940000159471; -.
DR HOGENOM; CLU_015166_14_2_1; -.
DR InParanoid; H0WTE8; -.
DR OMA; VWSNIIC; -.
DR TreeFam; TF323211; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0015078; F:proton transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:Ensembl.
DR GO; GO:1900407; P:regulation of cellular response to oxidative stress; IEA:Ensembl.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45618:SF20; BRAIN MITOCHONDRIAL CARRIER PROTEIN 1; 1.
DR PANTHER; PTHR45618; MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00784; MTUNCOUPLING.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..355
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003543908"
FT REPEAT 72..161
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 169..254
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 263..353
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 41..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 39965 MW; 0421463DAA451356 CRC64;
MGIFPGIILI FLRVKFATAA VIVNMRVHRI SGLEARAMEK IKSNRERAEK SRKREHQKSA
TVSHEMSGLN WKPFVYGGLA SIVAEFGTFP VDLTKTRLQV QGQSIDVRFK EIKYRGMFHA
LFRIYKEEGV LALYSGIAPA LLRQASYGTI KIGIYQSLKR LFVERLEDET LLINMICGVV
SGVISSTIAN PTDVLKIRMQ AQGSLFQGSM IGSFIDIYQQ EGTRGLWRGV VPTAQRAAIV
VGVELPVYDI TKKHLILSGM MGDTILTHFV SSFTCGLAGA LASNPVDVVR TRMMNQRAIV
GHVDVYKGTL DGILKMWKHE GFFALYKGFW PNWLRLGPWN IIFFITYEQL KRLQI
//
