ID   H0WXE6_OTOGA            Unreviewed;       672 AA.
AC   H0WXE6;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Glycerophosphocholine phosphodiesterase 1 {ECO:0000313|Ensembl:ENSOGAP00000007123.2};
GN   Name=GPCPD1 {ECO:0000313|Ensembl:ENSOGAP00000007123.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000007123.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000007123.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC       family. {ECO:0000256|ARBA:ARBA00007277}.
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DR   EMBL; AAQR03053722; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03053723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03053724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03053725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003788257.2; XM_003788209.2.
DR   AlphaFoldDB; H0WXE6; -.
DR   STRING; 30611.ENSOGAP00000007123; -.
DR   Ensembl; ENSOGAT00000007959.2; ENSOGAP00000007123.2; ENSOGAG00000007955.2.
DR   GeneID; 100942596; -.
DR   KEGG; oga:100942596; -.
DR   CTD; 56261; -.
DR   eggNOG; KOG2421; Eukaryota.
DR   GeneTree; ENSGT00440000033970; -.
DR   HOGENOM; CLU_013007_2_0_1; -.
DR   InParanoid; H0WXE6; -.
DR   OMA; LKVYHTA; -.
DR   OrthoDB; 1005457at2759; -.
DR   TreeFam; TF314722; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:2001070; F:starch binding; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   CDD; cd05814; CBM20_Prei4; 1.
DR   CDD; cd08607; GDPD_GDE5; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR013784; Carb-bd-like_fold.
DR   InterPro; IPR034839; CBM20_GPCPD1.
DR   InterPro; IPR002044; CBM_fam20.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR22958:SF1; GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1; 1.
DR   PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR   Pfam; PF00686; CBM_20; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   SMART; SM01065; CBM_2; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   SUPFAM; SSF49452; Starch-binding domain-like; 1.
DR   PROSITE; PS51166; CBM20; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          1..115
FT                   /note="CBM20"
FT                   /evidence="ECO:0000259|PROSITE:PS51166"
FT   DOMAIN          318..618
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
SQ   SEQUENCE   672 AA;  76081 MW;  C871D8991067148D CRC64;
     MTPSQVTFEI RGTLLPGEVF AICGSCDALG NWSPQNAVAL LPENEIGESM LWKATIVLSR
     GVSVQYRYFK GYFLEPKTIG GPCQVIVHKW ETHLQPRSIT PLENEITIDD GQFGIHNGVE
     TLDSGWLTCQ TEIRLRLHYS EKPPVSITKK KFKKSRFRVK LTLEGLEEDD DDRVSPTVLH
     KMSNSLEISL ISDHEFKCRH SQPECGYGLQ PDRWTEYSIQ TMEPDNLELI FDFFEEDLGE
     HVVQGDALPG HVGAACLLSS TIAESGKSAG ILTLPIMSRN SRKTIGKVRV DYIIIKPLPG
     YNCDMKFSYS KYWKPRTPLD VGHRGAGNST TTAQLAKVQE NTIASLRNAA SHGAAFVEFD
     VHLSKDFVPV VYHDLTCCLT MKKKFDADPA ELFEIPVKEL TFDQLQLLKL AHVTALKSKD
     RRESVVQEEN SFSENQPFPS LKMVLEALPE DVGFNIEIKW ICQQRDGMWD GNLSTYFDMN
     LFLDIILKTV LENSGKRRIV FSSFDADICT MVRQKQNKYP ILFLTQGKSD IYPELMDLRS
     RTTPIAMSFA QFENLLGINA HTEDLLRNPS YIQEAKAKGL VIFCWGDDTN DPENRRKLKE
     FGVNGLIYDR IYDWMPEQPN IFQVEQLERL KQELPELKSC LCPTVSRFAP SSLCGDPDIH
     VDANGIDNVE NA
//