ID H0WXX4_OTOGA Unreviewed; 269 AA.
AC H0WXX4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000007331.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000007331.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666}.
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DR EMBL; AAQR03160235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160236; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160239; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160240; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03160241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WXX4; -.
DR STRING; 30611.ENSOGAP00000007331; -.
DR Ensembl; ENSOGAT00000008194.2; ENSOGAP00000007331.2; ENSOGAG00000008190.2.
DR eggNOG; KOG1418; Eukaryota.
DR GeneTree; ENSGT00940000156560; -.
DR HOGENOM; CLU_1036409_0_0_1; -.
DR InParanoid; H0WXX4; -.
DR OMA; RCTENSI; -.
DR TreeFam; TF313947; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR003976; 2pore_dom_K_chnl_TREK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF21; POTASSIUM CHANNEL SUBFAMILY K MEMBER 2; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01499; TREKCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..38
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 79..155
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 269 AA; 30010 MW; C82EB58B9A409062 CRC64;
LGFGNISPRT EGGKIFCIIY ALLGIPLFGF LLAGVGDQLG TIFGKGIAKV EDTFIKWNVS
QTKIRIISTI IFILFGCVLF VALPAIIFKH IEGWSALDAI YFVVITLTTI GFGDYVAGGS
DIEYLDFYKP VVWFWILVGL AYFAAVLSMI GDWLRVISKK TKEEVGEFRA HAAEWTANVT
AEFKETRRRL SVEIYDKFQR ATSIKRKLSA ELAGNHNQEL TPCRRTLSVN HLTSERDVLP
PLLKTESIYL NGLTPHCAGE EIAVIENIK
//
