GenomeNet

Database: UniProt
Entry: H0WZ13_OTOGA
LinkDB: H0WZ13_OTOGA
Original site: H0WZ13_OTOGA 
ID   H0WZ13_OTOGA            Unreviewed;      1052 AA.
AC   H0WZ13;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   28-MAR-2018, entry version 38.
DE   SubName: Full=Cysteine rich transmembrane BMP regulator 1 {ECO:0000313|Ensembl:ENSOGAP00000007794};
GN   Name=CRIM1 {ECO:0000313|Ensembl:ENSOGAP00000007794};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;
OC   Lorisiformes; Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000007794, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Ensembl:ENSOGAP00000007794}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000007794}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAQR03122440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122448; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03122449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 30611.ENSOGAP00000007794; -.
DR   Ensembl; ENSOGAT00000008699; ENSOGAP00000007794; ENSOGAG00000008694.
DR   eggNOG; KOG1216; Eukaryota.
DR   eggNOG; ENOG410XNSK; LUCA.
DR   GeneTree; ENSGT00840000129763; -.
DR   InParanoid; H0WZ13; -.
DR   OMA; CPLPSRC; -.
DR   OrthoDB; EOG091G01IV; -.
DR   TreeFam; TF106451; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.
DR   GO; GO:0030165; F:PDZ domain binding; IEA:Ensembl.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   InterPro; IPR004094; Antistasin-like.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR011061; Hirudin/antistatin.
DR   InterPro; IPR000867; IGFBP-like.
DR   InterPro; IPR001007; VWF_dom.
DR   Pfam; PF02822; Antistasin; 4.
DR   Pfam; PF00219; IGFBP; 1.
DR   Pfam; PF00093; VWC; 6.
DR   SMART; SM00121; IB; 1.
DR   SMART; SM00214; VWC; 6.
DR   SMART; SM00215; VWC_out; 3.
DR   SUPFAM; SSF57184; SSF57184; 1.
DR   SUPFAM; SSF57262; SSF57262; 2.
DR   PROSITE; PS51252; ANTISTASIN; 4.
DR   PROSITE; PS51323; IGFBP_N_2; 1.
DR   PROSITE; PS01208; VWFC_1; 5.
DR   PROSITE; PS50184; VWFC_2; 6.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005225};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     45       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    956    976       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       50    129       IGFBP N-terminal. {ECO:0000259|PROSITE:
FT                                PS51323}.
FT   DOMAIN      351    408       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      418    474       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      486    515       Antistasin-like. {ECO:0000259|PROSITE:
FT                                PS51252}.
FT   DOMAIN      524    549       Antistasin-like. {ECO:0000259|PROSITE:
FT                                PS51252}.
FT   DOMAIN      556    581       Antistasin-like. {ECO:0000259|PROSITE:
FT                                PS51252}.
FT   DOMAIN      584    609       Antistasin-like. {ECO:0000259|PROSITE:
FT                                PS51252}.
FT   DOMAIN      623    680       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      694    752       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      768    826       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      823    890       VWFC. {ECO:0000259|PROSITE:PS50184}.
SQ   SEQUENCE   1052 AA;  115361 MW;  0BE913EA89B2C8E8 CRC64;
     QLLGHRAGSV RRAPRGGGGG GGGGGGLAGC GHLLVSLLGL LLLLARSGTR ALVCLPCDES
     KCEEPRSCPG SIVQGVCGCC YMCARQRNES CGGAYGLHGA CDRGLRCVIR PPLNGDSITE
     YEVGVCEDEN WDDDQLLGFE PCNENLISGC NIINGKCECD TIRTCNNPFE FPRKDMCLSA
     LKRIEEEKPD CSKARCEVQF SPRCPEDSVL IEGYAPPGEC CPLPSRCVCD PAGCLRKVCQ
     PGYLNILVSK ASGKPGECCD LYECKPVFSV DCSTVECPSV QQAVCPLDSY ETQVRLTADG
     CCTLPTRCEC LSGLCGFPVC EVGSTPRIVS RGDGTPGKCC DVFECVNETK PACVFNNVEY
     YDGDMFRMDN CRFCRCQGGV SICFTAQCGE LNCERYYVPE GECCPVCEDP VYPFNNPAGC
     YANGQIRAHG DRWREDDCTF CQCINGEPHC VATACGQSCM HPVKVPGECC PVCEEPTYIT
     IDPPACGELS NCTLTEKDCV YGFKLDHNGC RTCQCKNREE LCAGLKRGCT VECAFGFLTD
     AHNCEICQCR PRPRKCRPVI CDKHCPLGYL KNKHGCDICR CKKCPELPCS KICPLGFQQD
     SHGCLICKCR EVPASAGPPV LSGTCLSMDG HHHKNEESWH DGCRECYCHN GREMCALITC
     PVPTCGNPTI HPGQCCPSCA DDFVVQKPEL STPSICHAPG GEYFVEGETW NIDSCTQCTC
     HGGRVLCETE VCPPLLCQNP SRTQDSCCPQ CPDEPPRPSS PHNDSVPSYC KNEEGDIFLA
     AESWKPDVCT SCVCMDSVIS CYSESCPSVS CERPVLRKGQ CCPYCIGKTK IPRQIVFQGI
     MYMLHGRTRQ GLCYHCYCLQ GQTLCSTVSC PPLPCVEPIN VEGSCCPMCP EMYIPEATNI
     PIEKTNHRGE TDLEVPMWPT PGENDIHLPR DIGHLQVDYR DNNRLHPSED SPLDSVALVV
     VPIIICLSII IAFLFINQKK QWIPLLCWYR TPTKPSSLNN QLVSVDCKKG TRVQVESSQR
     MLRIAEPDAR FSGFYSMQKQ NHLQADNFYQ TV
//
DBGET integrated database retrieval system