ID H0X1D6_OTOGA Unreviewed; 460 AA.
AC H0X1D6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=F-box and WD repeat domain containing 2 {ECO:0000313|Ensembl:ENSOGAP00000008801.2};
GN Name=FBXW2 {ECO:0000313|Ensembl:ENSOGAP00000008801.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000008801.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000008801.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03035109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03035110; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03035111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 30611.ENSOGAP00000008801; -.
DR Ensembl; ENSOGAT00000009843.2; ENSOGAP00000008801.2; ENSOGAG00000009841.2.
DR eggNOG; KOG0274; Eukaryota.
DR GeneTree; ENSGT00930000151016; -.
DR HOGENOM; CLU_041488_0_0_1; -.
DR InParanoid; H0X1D6; -.
DR OMA; TIACWDW; -.
DR TreeFam; TF333134; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR CDD; cd22131; F-box_FBXW2; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR042627; FBXW2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44436; F-BOX/WD REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR44436:SF1; F-BOX_WD REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 54..101
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 235..269
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 460 AA; 53132 MW; 76982AA601FE8461 CRC64;
MERKDFETWL DNISVTFLSL TDLQKNETLD HLISLSGAVQ LRHLSNNLET LLKRDFLKLL
PLELSFYLLK WLDPQTLLTC CLVSKQWNKV ISACTEVWQT ACKNLGWQID DSVQDALHWK
KVYLKAILRM KQLEDHEAFE TSSLIGHSAR VYALYYKDGL LCTGKRHELE LVLCFLFLVC
LYFMGCKQKT VIFVKFYEKK SFTYSFKHNV NHWQXGLGIR TRHLRYHCQR LYALVFSVDY
NDELDILVSG SADFTVKVWA LSAGTCLNTL TGHTEWVTKV VLQKCKVKSL LHSPGDFILL
SADKYEIKIW PIGREINCKC LKTLSVSEDR SICLQPRLHF DGKYIVCSSA LGLYQWDFAS
YDILRVIKTP EIANLALLGF GDIFALLFDN RYLYIMDLRT ESLISRWPLP EYRKSKRGSS
FLAGEASWLN GLDGHNDTGL VFATSMPDHS IHLVLWKEHG
//
