ID H0X3B6_OTOGA Unreviewed; 365 AA.
AC H0X3B6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Replication factor C subunit 4 {ECO:0000313|Ensembl:ENSOGAP00000009604.2};
GN Name=RFC4 {ECO:0000313|Ensembl:ENSOGAP00000009604.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000009604.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000009604.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
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DR EMBL; AAQR03094666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03094667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03094668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012662366.1; XM_012806912.1.
DR AlphaFoldDB; H0X3B6; -.
DR STRING; 30611.ENSOGAP00000009604; -.
DR Ensembl; ENSOGAT00000010735.2; ENSOGAP00000009604.2; ENSOGAG00000010731.2.
DR GeneID; 100959346; -.
DR KEGG; oga:100959346; -.
DR CTD; 5984; -.
DR eggNOG; KOG0989; Eukaryota.
DR GeneTree; ENSGT00550000074917; -.
DR HOGENOM; CLU_042324_1_1_1; -.
DR InParanoid; H0X3B6; -.
DR OMA; GCQSGSF; -.
DR OrthoDB; 275853at2759; -.
DR TreeFam; TF314424; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0031390; C:Ctf18 RFC-like complex; IEA:Ensembl.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:Ensembl.
DR GO; GO:0031391; C:Elg1 RFC-like complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:Ensembl.
DR GO; GO:0017116; F:single-stranded DNA helicase activity; IEA:Ensembl.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:Ensembl.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013748; Rep_factorC_C.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF20; REPLICATION FACTOR C SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 71..203
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 39927 MW; CAD65A25179331D7 CRC64;
MQAFLKGTSI STKPPVTKDH RGVAATAGSS GENKKAKPVP WVEKYRPKSV DEVAFQDEVV
AVLKKSLEGA DLPNLLFYGP PGTGKTSTIL AAARELFGPE LFRLRVLELN ASDERGIQVI
REKVKNFAQL TVSGSRSDGK LCPPFKIVIL DEADSMTSAA QAALRRTMEK ESKTTRFCLI
CNYVSRIIEP LTSRCSKFRF KPLSDKIQQQ RLLNITEKEN VKISSEGIAY LVKVSEGDLR
KAITFLQSAT RLTGGKEITE EVITDIAGVI PSETIDGVFA ACQSGSFDKL ETVVKDLIIE
GHAATQLVNQ LHDVVVENDT LSDKQKSIIT EKLAEADKCL ADGADEHLQL ISLCATVMQQ
LTQNC
//
