ID H0X3P6_OTOGA Unreviewed; 601 AA.
AC H0X3P6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Myelin expression factor 2 {ECO:0000313|Ensembl:ENSOGAP00000009767.2};
GN Name=MYEF2 {ECO:0000313|Ensembl:ENSOGAP00000009767.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000009767.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000009767.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQR03024514; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003784378.2; XM_003784330.2.
DR AlphaFoldDB; H0X3P6; -.
DR STRING; 30611.ENSOGAP00000009767; -.
DR Ensembl; ENSOGAT00000010914.2; ENSOGAP00000009767.2; ENSOGAG00000010907.2.
DR GeneID; 100942779; -.
DR KEGG; oga:100942779; -.
DR CTD; 50804; -.
DR eggNOG; ENOG502QV3I; Eukaryota.
DR GeneTree; ENSGT00940000157397; -.
DR HOGENOM; CLU_019566_1_0_1; -.
DR InParanoid; H0X3P6; -.
DR OMA; EKSPVIY; -.
DR OrthoDB; 317787at2759; -.
DR TreeFam; TF313406; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12658; RRM1_MYEF2; 1.
DR CDD; cd12660; RRM2_MYEF2; 1.
DR CDD; cd12662; RRM3_MYEF2; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR034630; MYEF2_RRM1.
DR InterPro; IPR034631; MYEF2_RRM3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23003:SF15; MYELIN EXPRESSION FACTOR 2; 1.
DR PANTHER; PTHR23003; RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 101..179
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 234..311
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 524..600
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 64393 MW; 25EA332663986EB9 CRC64;
MADADKPEVP GATGKDSPHQ QSAEPPGESR REPHPPEAEK QQPQPLGSSS NGVKMENDES
VKEEKSDLKE KSTGNKKANR FHPYSKDKNS GTGEKKGPNR NRVFISNIPY DMKWQAIKDL
MREKVGEVTY VELFKDAEGK SRGCGVVEFK DEEFVKKALE TMNKYDLSGR PLNIKEDPDG
ENARRALQRT GGSFPGGHVP DMGSGLMNLP PSILNNPNIP PEVISNLQAG RLGSTIFVAN
LDFKVGWKKL KEVFSIAGTV KRADIKEDKD GKSRGMGTVT FEQAIEAVQA ISMFNGQFLF
DRPMHVKMDD KSVPHEEYRS HDSKTPQLPR GLGGIGMGLG PGGQPISASQ LNIGGVMGNL
GPSGMGMDGP GFGGMNRIGG GIGFGGLEAM NSMGGFGGVG RMGELYRGAM TSSMEREFGR
GDIGINRGFG DSFGRLGSAM IGGFAGRIGA SNMGPVGSGI SGGMGGMNSV TGGMGIGLDR
MSSSFDRMGP GIGAILERSI DMDRGFLSGP MGSGMRDRIG SKGNQIFVRN LPFDLTWQKL
KEKFSQCGHV MFAEIKMENG KSKGCGTVRF DSPESAEKAC RIMNGIKISG REIDVRLDRN
A
//
