ID H0X5P1_OTOGA Unreviewed; 1144 AA.
AC H0X5P1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=RHO family interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSOGAP00000010613.2};
GN Name=RIPOR1 {ECO:0000313|Ensembl:ENSOGAP00000010613.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000010613.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000010613.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RIPOR family.
CC {ECO:0000256|ARBA:ARBA00005744}.
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DR EMBL; AAQR03153062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012666582.1; XM_012811128.1.
DR AlphaFoldDB; H0X5P1; -.
DR STRING; 30611.ENSOGAP00000010613; -.
DR Ensembl; ENSOGAT00000011867.2; ENSOGAP00000010613.2; ENSOGAG00000011861.2.
DR GeneID; 100962099; -.
DR KEGG; oga:100962099; -.
DR CTD; 79567; -.
DR eggNOG; ENOG502QQ7T; Eukaryota.
DR GeneTree; ENSGT00940000153717; -.
DR HOGENOM; CLU_006211_0_0_1; -.
DR InParanoid; H0X5P1; -.
DR OMA; LPCIFGP; -.
DR OrthoDB; 2909587at2759; -.
DR TreeFam; TF329332; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0071889; F:14-3-3 protein binding; IEA:Ensembl.
DR GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR GO; GO:0051683; P:establishment of Golgi localization; IEA:Ensembl.
DR GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR GO; GO:0090316; P:positive regulation of intracellular protein transport; IEA:Ensembl.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:Ensembl.
DR GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR031780; FAM65_N.
DR InterPro; IPR026136; RIPOR3.
DR PANTHER; PTHR15829; PROTEIN KINASE PKN/PRK1, EFFECTOR; 1.
DR PANTHER; PTHR15829:SF1; RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1; 1.
DR Pfam; PF15903; PL48; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 17..365
FT /note="FAM65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15903"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1144 AA; 124806 MW; ED9E0240BF532A0E CRC64;
MMSLSVRPQR RPLSARVSRS QSFAGVLGSH ERGPRNLPVF SPPGPPRKLP ALSRVSRMFS
VAHPASKVPQ PERLDLVYAA LKQGLTAYLE VHQQEQEKLQ VQIRESKRNS RLGFLYDLDK
QVKSIERFLR RLEFHASKID ELYEAYCVQR RLRDGAYNMV RAYSTGSPGS REARDSLAEA
TRGHREYTES MCLLESELEA QLGEFHLRMK GLAGFARLCV GDQYEICMKY GRQRWKLRGR
IEGSGKQVWD SEETIFLPLL TEFLSIKVTE LKGLANHVIV GSVSCETKDL FAALPQVVAV
DINDLGTIKL SLEVTWSPFD KDDQPSTAST VNKASTVTKR FSTYSQSPPD TPSLREQAFY
NMLRRQEELE NGTAWSLSSE SSDDSSSPQL SGTARHSSAP RPLVQQPEPL PIQVAFRRPE
TPSSRSLDEE GAMAPALANG HAPYSRTLSH ISEASVDAAL AEASVEAVGL ESLVQGPSPP
VYLDPTHREH PSPIPPALDS GHSATSPTLG TSGPASKFTD PAPSLDSVQE NTDSGPLELP
GPTHTTTDST YSAISPTHSA PTLTHTTASS TYHKPMISTL TTIGPCPTIT SPVQTTASPT
HTTASPTHTT ESPTHTTKNP THTTTSPTHT VTSPTPASTT CIQPAPRALS TSDQSPSCSS
RKPFTNPVPD LPESIIQRLT PPASPLSPLP QHSDLTLAVA AQAPVSGEAG ETGDRRLEEA
LGALTAALDD YRGQFPELQG LEQEVTRLES LLMQRQGLTR SRASSLSITV EHALESFSFL
NEDEDNDGPS DRLPSSPEAG AEDSLESPSA RPLSTGCPAL DSALVQHLYH CSRLLLKLGT
FGPLRCQEAW ALERLLREAR VLEAVCELSR LWEIPVTSAQ EVVQFSASRP GFLTFWDQCT
QGLGPFLCPV ERVLLTFCNQ YGARLSLRQP GLAEAVCVKF LEDALGQKLP RRPQPGPGEH
LTIFQFWSYV ETLDSPSMEA YVTETAEEVL LVQNLNSDDQ AVVLKALRLA PEGRLRRDGL
RALSSLLVHG NNKVMAAVST QLRSLSLGPT FRERALLCFL DQLEDEDVQT RVAGCLALGC
IKAPEGIEPL VYLCQTDTEA VREAARQSLQ QCGEEGQSAH RRLEETLDAL PRIFGPGSMA
STAF
//
