ID   H0X798_OTOGA            Unreviewed;       582 AA.
AC   H0X798;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=SHOC2 leucine rich repeat scaffold protein {ECO:0000313|Ensembl:ENSOGAP00000011275.2};
GN   Name=SHOC2 {ECO:0000313|Ensembl:ENSOGAP00000011275.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000011275.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000011275.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AAQR03046887; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03046888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03046889; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03046890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03046891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03046892; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003787217.1; XM_003787169.2.
DR   AlphaFoldDB; H0X798; -.
DR   SMR; H0X798; -.
DR   STRING; 30611.ENSOGAP00000011275; -.
DR   Ensembl; ENSOGAT00000012590.2; ENSOGAP00000011275.2; ENSOGAG00000012588.2.
DR   GeneID; 100946187; -.
DR   KEGG; oga:100946187; -.
DR   CTD; 8036; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   GeneTree; ENSGT00940000156270; -.
DR   HOGENOM; CLU_000288_18_23_1; -.
DR   InParanoid; H0X798; -.
DR   OMA; NQFTSYP; -.
DR   OrthoDB; 643105at2759; -.
DR   TreeFam; TF315742; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0000164; C:protein phosphatase type 1 complex; IEA:Ensembl.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR48051; -; 1.
DR   PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR   Pfam; PF13855; LRR_8; 5.
DR   SMART; SM00364; LRR_BAC; 12.
DR   SMART; SM00365; LRR_SD22; 6.
DR   SMART; SM00369; LRR_TYP; 16.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS51450; LRR; 7.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          1..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   582 AA;  64888 MW;  F3F828646642A855 CRC64;
     MSSSLGKEKD SKEKDPKVPS AKEREKEAKA SGGFGKESKE KEPKTKGKDA KDGKKDSSAA
     QPGVAFSVDN TIKRPNPAPG TRKKSSNAEV IKELNKCREE NSMRLDLSKR SIHILPSSIK
     ELTQLTELYL YSNKLQSLPA EVGCLVNLMT LALSENSLTS LPDSLDNLKK LRMLDLRHNK
     LREIPSVVYR LDSLTTLYLR FNRITTVEKD IKNLSKLSML SIRENKIKQL PAEIGELCNL
     ITLDVAHNQL EHLPKEIGNC TQITNLDLQH NELLDLPDTI GNLSSLSRLG LRYNRLSAIP
     RSLAKCSALE ELNLENNNIS TLPESLLSSL VKLNSLTLAR NCFQLYPVGG PSQFSTIYSL
     NMEHNRINKI PFGIFSRAKV LSKLNMKDNQ LTSLPLDFGT WTSMVELNLA TNQLTKIPED
     VSGLVSLEVL ILSNNLLKKL PHGLGNLRKL RELDLEENKL ESLPNEIAYL KDLQKLVLTN
     NQLTTLPRGI GHLTNLTHLG LGENLLTHLP EEIGTLENLE ELYLNDNPNL HSLPFELALC
     SKLSIMSIEN CPLSHLPPQI VAGGPSFIIQ FLKMQGPYRA MV
//