ID H0X9Y1_OTOGA Unreviewed; 803 AA.
AC H0X9Y1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Tetratricopeptide repeat domain 7B {ECO:0000313|Ensembl:ENSOGAP00000012402.2};
GN Name=TTC7B {ECO:0000313|Ensembl:ENSOGAP00000012402.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000012402.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000012402.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03046076; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046077; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046078; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046079; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046080; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046084; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03046085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0X9Y1; -.
DR STRING; 30611.ENSOGAP00000012402; -.
DR Ensembl; ENSOGAT00000013850.2; ENSOGAP00000012402.2; ENSOGAG00000013839.2.
DR eggNOG; KOG4162; Eukaryota.
DR GeneTree; ENSGT00940000158474; -.
DR HOGENOM; CLU_010512_1_0_1; -.
DR InParanoid; H0X9Y1; -.
DR OMA; YNRAERW; -.
DR TreeFam; TF313783; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR045819; TTC7_N.
DR PANTHER; PTHR23083:SF365; TETRATRICOPEPTIDE REPEAT PROTEIN 7B; 1.
DR PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 2.
DR Pfam; PF19440; TTC7_N; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..346
FT /note="Tetratricopeptide repeat protein 7 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19440"
FT REPEAT 357..390
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 690..723
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 758..791
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 803 AA; 89738 MW; F6AED2F3D8548221 CRC64;
DDMAELLLGE SKLEQYLKEY PLRQGASPRG PRPQLTEVRK HLTAALDRGN LKSEFLQESN
LIMAKLNYVE GDYKEALNIY ARVGLDDLPL TASPPYRLRV IAEAYATKGL CLEKLPISSS
TSNLHVDWEQ DVITCYEKAG DIALLYLQEI ERVILTNIQN RSPKPGPAPH DQELGFFLET
GLQRAHVLYF KNGNLTRGVG RFREILRAVE TRTTQNLRMT IARQLAEILL RGMCEQSYWN
PLEEPPCQSP LDDPLRKGAN TKTYTLTRRA RVYSGENIFC PQENTEEALL LLLISESMAN
RDAVLSRIPE HKSDRLISLQ SASVVYDLLT IALGRRGQYE MLSECLERAM KFAFEEFHLW
YQFALSLMAA GKSARAVKVL KECIRLKPDD ATIPLLAAKL CMGSLHWLEE AEKFAKTVVD
VGEKTSEFKA KGYLALGLTY SLQATDASLR GMQEVLQRKA LLAFQRAHSL SPTDHQAAFY
LALQLAISRQ IPEALGYVRQ ALQLQGDDVN SLHLLALLLS AQKHYHDALN IIDMALSEYP
ENFILLFSKV KLESLCRGPD EALLTCKHML QIWKSCYNLT NPSDSGRGSS LLDRTIADRR
QLNTITLPDF SDPETGSVHA TSVAASRVEQ ALSEVASSLQ SSAPKQGPLH PWMTLAQIWL
HAAEVYIGIG KPAEATACTQ EAANLFPMSH NVLYMRGQVA ELRGNMDEAR RWYEEALSIS
PTHVKSMQRL ALILHQLGRY SLAEKILRDA VQVNSTAHEV WNGLGEVLQA QGNDAAATEC
FLTALELEAS SPAVPFTIIP RVL
//
