ID H0XAR7_OTOGA Unreviewed; 562 AA.
AC H0XAR7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=nucleoside-diphosphate kinase {ECO:0000256|ARBA:ARBA00012966};
DE EC=2.7.4.6 {ECO:0000256|ARBA:ARBA00012966};
GN Name=AK5 {ECO:0000313|Ensembl:ENSOGAP00000012732.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000012732.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000012732.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the adenylate kinase family.
CC {ECO:0000256|ARBA:ARBA00007220, ECO:0000256|RuleBase:RU003330}.
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DR EMBL; AAQR03023553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023557; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023558; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023560; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023561; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03023562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003784265.1; XM_003784217.1.
DR AlphaFoldDB; H0XAR7; -.
DR STRING; 30611.ENSOGAP00000012732; -.
DR Ensembl; ENSOGAT00000014212.2; ENSOGAP00000012732.2; ENSOGAG00000014208.2.
DR GeneID; 100945641; -.
DR KEGG; oga:100945641; -.
DR CTD; 26289; -.
DR eggNOG; KOG3079; Eukaryota.
DR GeneTree; ENSGT00940000155917; -.
DR HOGENOM; CLU_034712_1_0_1; -.
DR InParanoid; H0XAR7; -.
DR OMA; NGLVHIC; -.
DR OrthoDB; 1330004at2759; -.
DR TreeFam; TF313747; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0004017; F:adenylate kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0046034; P:ATP metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 2.
DR CDD; cd22978; DD_AK5; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_00235; Adenylate_kinase_Adk; 2.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR033690; Adenylat_kinase_CS.
DR InterPro; IPR006267; AK1/5.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01360; aden_kin_iso1; 1.
DR PANTHER; PTHR23359:SF79; ADENYLATE KINASE ISOENZYME 5; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 2.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00113; ADENYLATE_KINASE; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003330};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003330}.
SQ SEQUENCE 562 AA; 63345 MW; 0813FD9E754A61AC CRC64;
MNTSDAKEYL ARREIPQLFE SLLNGLMCSK PEDPIEYLEG CLQKVKELGG CDKVKWDTFV
SQEKKTLPPL NGGQPRRSFL RNVMPENSNF SYRRYDRLPP IHQFSIESDT DLSETAELIE
EYEVFDPTRP RPKIILVIGG PGSGKGTQSL KIAERYGFQY ISVGELLRKR IHSASSNRKW
SLIAKIITTG ELAPQETTIT EIKQKLMQIP DEEGIVIDGF PRDVAQALSF EDQICTPDLV
VFLACANQRL KERLLKRAEQ QGRPDDNLKA TQRRLMNFKQ NAAPLVKYFQ EKGLIMTFDA
DRDEDEVFYD ISVAVDSKLF PNKEAAAGSS DLDPSMMLEP GEIIDTGSDY EDQGDDHLHV
FGEDTLGGFM EDLRKCKIIF MIGGPGSGKG TQCEKLVEKY GFTHLSTGEL LRHELASESE
RSKLIRDIME RGDLVPSGIV LELLKEAMVA SLGDTRGFLI DGYPREVRQG EEFGRRIGDP
HLVICMDCSA DTMTNRLLQR SQSSPQADDA PKTIARRLEA YYRAAIPVIA YYETRTQIQK
INAEGTPEEV FLQLCKAIDS IF
//
