ID   H0XBT7_OTOGA            Unreviewed;       576 AA.
AC   H0XBT7;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=FGGY carbohydrate kinase domain containing {ECO:0000313|Ensembl:ENSOGAP00000013192.2};
GN   Name=FGGY {ECO:0000313|Ensembl:ENSOGAP00000013192.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000013192.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000013192.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
CC       {ECO:0000256|ARBA:ARBA00009156}.
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DR   EMBL; AAQR03100477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100485; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03100486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0XBT7; -.
DR   STRING; 30611.ENSOGAP00000013192; -.
DR   Ensembl; ENSOGAT00000014726.2; ENSOGAP00000013192.2; ENSOGAG00000014721.2.
DR   eggNOG; KOG2517; Eukaryota.
DR   GeneTree; ENSGT01000000214434; -.
DR   HOGENOM; CLU_009281_10_2_1; -.
DR   InParanoid; H0XBT7; -.
DR   OMA; HKAMWHE; -.
DR   TreeFam; TF300904; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0019150; F:D-ribulokinase activity; IEA:Ensembl.
DR   GO; GO:0070050; P:neuron cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0019321; P:pentose metabolic process; IEA:Ensembl.
DR   CDD; cd07782; FGGY_YpCarbK_like; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; FGGY_C.
DR   InterPro; IPR018484; FGGY_N.
DR   InterPro; IPR006003; FGGY_RbtK-like.
DR   NCBIfam; TIGR01315; 5C_CHO_kinase; 1.
DR   PANTHER; PTHR43435:SF4; FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43435; RIBULOKINASE; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          11..267
FT                   /note="Carbohydrate kinase FGGY N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00370"
FT   DOMAIN          289..521
FT                   /note="Carbohydrate kinase FGGY C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02782"
SQ   SEQUENCE   576 AA;  62657 MW;  D6B0AB2DF6483F1E CRC64;
     MSGRELEPAR YYVGVDVGTG SVRAALVDQS GIILAFADQP IKKWEPQFDH HEQSSEDIWA
     ACCAVTKKVV QGIDLNQIRG LGFDATCSLV ILDKQFRPLP VNHEGDSHRN IIMWLDHRAV
     SQVHRINATR HSVLRYIGGV MSVEMQAPKL LWLKENLRET CWDKAGHFFD LPDFLSWKAT
     GVTARSLCSL VCKWTYSAEK GWDDSFWKMV GLEDIVADNY NKIGNQVLPP GAALGNGLTP
     EAARDLGLPV GTAVAASLID AHAGGLGVIG ADVRGHGLVC EGQPVTSRLA VICGTSSCHM
     GISKDPIFVP GVWGPYFSAM VPGFWLNEGG QSITGKLIDH MVQGHAAFSE LQAKATARCQ
     SVYAYLNSHL DLIKKAQPVG FLTVDLHVWP DFHGNRSPLA DLTLKGMVSN SQWLLLPTVT
     AGRCPSLTLS PWVTGLKLSQ DLDDLAILYL ATVQAIAFGT RFIIEAMEAA GHSISTLFLC
     GGLSKNPLFV QMHADITGMP VVLSQEVESV LVGAAILGAC ASGDFASVQE AMAKMSKVGK
     VVFPRQEDKR YYDKKYQVFL RLVEHQKEYA AIMGGD
//