ID H0XC83_OTOGA Unreviewed; 1043 AA.
AC H0XC83;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=CAP-Gly domain containing linker protein 2 {ECO:0000313|Ensembl:ENSOGAP00000013373.2};
GN Name=CLIP2 {ECO:0000313|Ensembl:ENSOGAP00000013373.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000013373.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000013373.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03108356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03108357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03108358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03108359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03108360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XC83; -.
DR STRING; 30611.ENSOGAP00000013373; -.
DR Ensembl; ENSOGAT00000014937.2; ENSOGAP00000013373.2; ENSOGAG00000014933.2.
DR eggNOG; KOG4568; Eukaryota.
DR GeneTree; ENSGT00940000159426; -.
DR HOGENOM; CLU_001753_0_0_1; -.
DR InParanoid; H0XC83; -.
DR OMA; GTQYFAC; -.
DR TreeFam; TF326096; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0035371; C:microtubule plus-end; IEA:Ensembl.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:Ensembl.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916:SF10; CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2; 1.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR Pfam; PF01302; CAP_GLY; 2.
DR SMART; SM01052; CAP_GLY; 2.
DR SUPFAM; SSF74924; Cap-Gly domain; 2.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS00845; CAP_GLY_1; 2.
DR PROSITE; PS50245; CAP_GLY_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 99..141
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 239..281
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1018..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 354..525
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 564..612
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 675..800
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 825..887
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 936..1003
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 18..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1043 AA; 115451 MW; CB4D90AFC015D2A9 CRC64;
MQKPSGLKPP GRGGKHSSPV GRTSTGSASA SAAAATTGSK EGSPLHKQAS SSSSSPAATA
PEKPGPKVAE VGDDFLGDFV LGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDTHS VESLTAQNLS LHSGTATPPL
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGDKDLR LGDRVLVGGT KTGVVRYVGE
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL
VDSVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE TQTQLEHARI GELEQSLLLE
KAQAERLLRE LADNRLTTVA EKSRVMQLEE ELSLRRGEIE ELQQCLLHSG PPPPDHPDAA
EILRLRERLL SASKEHQRES GVLRDKYEKA LKAYQVEVDK LRAANDKYAQ EVADLKDKVQ
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLSSGPG AQQKEIGELK AVMEGIKMEH
QLELGNLRAK HDLEMAVHVK EKEALRQRLQ EAQEEVAGLR QHWRAQLEAQ AGQHRLELQE
AQDQRRDAEL RVHELEKLDA EYRGQAQAIE FLKEQISLAE KKMLDYELLQ RAEAQSKQEA
ERLREKLLVA ENRLQALEAL CASQHSHVIE SNSISEETIR TKETLEGLQD KLNKRDKEVT
ALTSQTEMLR AQVSALESKC KSGEKKVDAL LKEKRRLEAE LEAVSRKTHD ASGQLVLLSQ
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL
DKEKSLSEQR RYSLIDPSSA PELLRLQHQL MSTEDALRDA LDQSQQVEKL MEAMRSCPDK
AQTIANSSSA NGIHQQDKAH KQE
//
