ID H0XEV5_OTOGA Unreviewed; 370 AA.
AC H0XEV5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Threonine synthase-like 2 {ECO:0000256|ARBA:ARBA00021942};
GN Name=THNSL2 {ECO:0000313|Ensembl:ENSOGAP00000014501.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000014501.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000014501.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
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DR EMBL; AAQR03151131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151133; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003799278.1; XM_003799230.2.
DR AlphaFoldDB; H0XEV5; -.
DR STRING; 30611.ENSOGAP00000014501; -.
DR Ensembl; ENSOGAT00000016199.2; ENSOGAP00000014501.2; ENSOGAG00000016194.2.
DR GeneID; 100963660; -.
DR KEGG; oga:100963660; -.
DR CTD; 55258; -.
DR eggNOG; KOG2616; Eukaryota.
DR GeneTree; ENSGT00940000158503; -.
DR HOGENOM; CLU_015170_1_1_1; -.
DR InParanoid; H0XEV5; -.
DR OMA; FDDCQDM; -.
DR OrthoDB; 275600at2759; -.
DR TreeFam; TF329641; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:Ensembl.
DR GO; GO:0070905; F:serine binding; IEA:Ensembl.
DR GO; GO:0046360; P:2-oxobutyrate biosynthetic process; IEA:Ensembl.
DR GO; GO:0016311; P:dephosphorylation; IEA:Ensembl.
DR GO; GO:0009071; P:serine family amino acid catabolic process; IEA:Ensembl.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR42690; THREONINE SYNTHASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42690:SF1; THREONINE SYNTHASE-LIKE 2; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 8..220
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 370 AA; 41083 MW; 3341A610AA7EB4C2 CRC64;
DLSLSCTAQF LQYFLEKREK HITVVVGTSG DTGSAAIESV QGAKNVDIIV LLPKGHCSKI
QELQMTTVLK ENVHVFGVEG NSDELDEPIK AVFADVAFVK KHHLMSLNSI NWSRVLVQMA
HYFFAYFRCA PSLDTHPLPP VEVVVPTGAA GNLAAGCIAQ KMGLPIRLVV AVNRNDIIHR
TIQRGDFSLS EAVTPTLASA MDIQVPYNME RIFWLLSGSN SQVTRILMEQ FERTQSLNLP
KELHSKLSES VTSESVSDDT ITKTMCRCWA ENQYLLCPHS AVAVSYHYQQ VDKQQPSVPR
CCLAPASAAK FPEVVLAAGL FPETPAEILA LDHKETCCTP MRRADNWTQM LRDTIEDLSQ
QWRARGLNSE
//
