ID H0XFZ4_OTOGA Unreviewed; 321 AA.
AC H0XFZ4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000014968.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000014968.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03078129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03078130; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03078131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03078132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XFZ4; -.
DR STRING; 30611.ENSOGAP00000014968; -.
DR Ensembl; ENSOGAT00000016728.2; ENSOGAP00000014968.2; ENSOGAG00000016723.2.
DR eggNOG; KOG3627; Eukaryota.
DR GeneTree; ENSGT00940000163636; -.
DR HOGENOM; CLU_006842_0_4_1; -.
DR InParanoid; H0XFZ4; -.
DR OMA; FQWIRRV; -.
DR TreeFam; TF351676; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24253:SF79; SERINE PROTEASE 41; 1.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU363034}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..321
FT /note="Peptidase S1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003544915"
FT DOMAIN 53..294
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 321 AA; 36059 MW; 3CA19208B49CF4A6 CRC64;
MGLWAGILLL VLLLVLGSQG KPGELRSAAA GSLSQKTVLL SWPCGHRDIH SLVVGGVETV
RGRWPWQALV QVPQGYFCGA SLLSRRWVLS AAHCFIKYNN PSKWWVQFGE LTLKPSLWNP
RVYLNRYRVQ DIIVNPSFHD GRNDIALLRL ASSVTYNKYI KPICVLSSTS MFQHRKDCWV
TGWGVLNENQ TYLPPPYNLQ EVKVTILNNT RCNYLFKQPS DRSVIQDSMI CAGAEDGSVD
TCKGDSGGPL VCDKDGLWYQ VGIVSWGMGC GRPNRPGIYT NISVYFDWIQ KLTSYSTPRL
DPSRLLLLLA LLWSPQLLQL V
//
