ID H0XJ43_OTOGA Unreviewed; 194 AA.
AC H0XJ43;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=nucleoside-diphosphate kinase {ECO:0000256|ARBA:ARBA00012966};
DE EC=2.7.4.6 {ECO:0000256|ARBA:ARBA00012966};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000016133.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000016133.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adenylate kinase family.
CC {ECO:0000256|ARBA:ARBA00007220, ECO:0000256|RuleBase:RU003330}.
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DR EMBL; AAQR03141050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03141051; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03141052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03141053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XJ43; -.
DR STRING; 30611.ENSOGAP00000016133; -.
DR Ensembl; ENSOGAT00000027910.1; ENSOGAP00000016133.1; ENSOGAG00000030767.1.
DR eggNOG; KOG3079; Eukaryota.
DR GeneTree; ENSGT00940000163693; -.
DR HOGENOM; CLU_032354_0_3_1; -.
DR InParanoid; H0XJ43; -.
DR OMA; MVIVFDC; -.
DR TreeFam; TF313747; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009123; P:nucleoside monophosphate metabolic process; IEA:UniProt.
DR GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00235; Adenylate_kinase_Adk; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR033690; Adenylat_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF57; NUCLEOSIDE-DIPHOSPHATE KINASE; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 1.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00113; ADENYLATE_KINASE; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003330};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003330}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..194
FT /note="nucleoside-diphosphate kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003546051"
SQ SEQUENCE 194 AA; 21757 MW; 57BEA18696001956 CRC64;
TTDILKSVLI IFVMGGPGSG KGTQCKYMAT KYGLYHVGLG QLLRQEAQRG TQRGRQIHDF
MLQGLLVPTG IILDMVSENM LSHPECQGFL IDGFPRELKQ AQEFELIVGR APNAVIVFDC
SMETMVRRLL GRGKVEHRAD DSESAIQRRL ETHYTLCEPV LTFYQQKNLL RNILAEAAPE
NIFAKCCSVI ESLQ
//
