ID H0XT25_OTOGA Unreviewed; 436 AA.
AC H0XT25;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Potassium voltage-gated channel modifier subfamily G member 3 {ECO:0000313|Ensembl:ENSOGAP00000019267.1};
GN Name=KCNG3 {ECO:0000313|Ensembl:ENSOGAP00000019267.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000019267.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000019267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAQR03051082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051084; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051086; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051087; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051088; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051089; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051090; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03051091; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003787922.1; XM_003787874.2.
DR AlphaFoldDB; H0XT25; -.
DR STRING; 30611.ENSOGAP00000019267; -.
DR Ensembl; ENSOGAT00000032912.1; ENSOGAP00000019267.1; ENSOGAG00000031627.1.
DR GeneID; 100963403; -.
DR KEGG; oga:100963403; -.
DR CTD; 170850; -.
DR eggNOG; KOG3713; Eukaryota.
DR GeneTree; ENSGT00940000159658; -.
DR HOGENOM; CLU_011722_4_1_1; -.
DR InParanoid; H0XT25; -.
DR OMA; FYNEMVY; -.
DR OrthoDB; 1478695at2759; -.
DR TreeFam; TF313103; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR GO; GO:0005251; F:delayed rectifier potassium channel activity; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18422; BTB_POZ_KCNG3; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003971; K_chnl_volt-dep_Kv9.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF91; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 3; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01494; KV9CHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 168..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..119
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 436 AA; 49528 MW; CC766190C6E79342 CRC64;
MTFGRSGAAS VVLNVGGARY SLSRELLKDF PLRRVSRLHG CRSERDVLEV CDDYDRERNE
YFFDRHSEAF GFILLYVRGH GKLRFAPRMC ELSFYNEMIY WGLEGAHLEY CCQRRLDDRM
SDTYTFYSAD EPGLLGRDEA RPGGAEAAPS RRWLERMRRT FEEPTSSLAA QILASVSVVF
VIVSMVVLCA STLPDWRAAA ADNRSLDDRS RYSAVPGREP SGIIEAICIG WFTAECIVRF
IISKNKCEFV KRPLNIIDLL AITPYYISVL MTVFTGENSQ LQRAGVTLRV LRMMRIFWVI
KLARHFIGLQ TLGLTLKRCY REMVMLLVFI CVAMAIFSAL SQLLEHGLDL ETSNKDFASI
PAACWWVIIS MTTVGYGDMY PITVPGRILG GVCVVSGIVL LALPITFIYH SFVQCYHELK
FRSVRCSRSL SAEFLN
//
