ID H0XTI9_OTOGA Unreviewed; 470 AA.
AC H0XTI9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Cytochrome P450 family 2 subfamily T member 1 {ECO:0000313|Ensembl:ENSOGAP00000019431.1};
GN Name=CYP2T1 {ECO:0000313|VGNC:VGNC:82766};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000019431.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000019431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
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DR EMBL; AAQR03177279; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03177280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XTI9; -.
DR STRING; 30611.ENSOGAP00000019431; -.
DR Ensembl; ENSOGAT00000029968.1; ENSOGAP00000019431.1; ENSOGAG00000032352.1.
DR VGNC; VGNC:82766; CYP2T1.
DR eggNOG; KOG0156; Eukaryota.
DR GeneTree; ENSGT00940000164086; -.
DR HOGENOM; CLU_001570_22_3_1; -.
DR InParanoid; H0XTI9; -.
DR OMA; FHDNFRI; -.
DR TreeFam; TF352043; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR PANTHER; PTHR24300:SF84; CYTOCHROME P450, FAMILY 2, SUBFAMILY T, POLYPEPTIDE 4; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..470
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003546060"
SQ SEQUENCE 470 AA; 51629 MW; 779AF338B9B01A96 CRC64;
MITGIAAALL LPLLVLALAW WSWGARCTQM RGALPPGPRP LPLLGNLLQL KPHLDRALME
LSRHWGSVFT VRLGRRPAVV LCGYAALRDA LVLQADTFSG RGAMPVFERF THGNGIVFSN
GPLWGALRNF ALGALKEFGL GTQTIEEQIL EEASCLLNEF QATIGTPFDP RRLLSNAVSN
VICSVVFGKR YSYGDSEFLR LLDLFNDNFR IMSSRWGEAK PSVPSKMTKN YSSDLKRKKH
LNETVLGSAC GSVRRAQAQY TGSTQRWQVC KLEKPRMGAW GLGMAGGVGK CSADQLPLAP
AKVQAELDAV VGRVRAPNLE DRACLPYTNA VLHEIQRFIS VLPLGLPRAL TRDTHLHGHF
LPKGTFVIPL LVSAHRDPTQ FKDPDCFNPT NFLNDKGEFQ SNDAFMPFAP GKRMCLGAGL
AHSEIFLFPT AILQKFSLLP VENSANINLT PHCTGLGNVP PAFQLRLVPR
//
