ID   H0XUV2_OTOGA            Unreviewed;       425 AA.
AC   H0XUV2;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Aminotransferase class I/classII domain-containing protein {ECO:0000259|Pfam:PF00155};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000019894.1, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000019894.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; AAQR03016671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0XUV2; -.
DR   STRING; 30611.ENSOGAP00000019894; -.
DR   Ensembl; ENSOGAT00000035020.1; ENSOGAP00000019894.1; ENSOGAG00000026542.1.
DR   eggNOG; KOG0634; Eukaryota.
DR   GeneTree; ENSGT00390000004594; -.
DR   HOGENOM; CLU_017584_0_6_1; -.
DR   InParanoid; H0XUV2; -.
DR   OMA; ARVFVCQ; -.
DR   TreeFam; TF328598; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProt.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR42790; AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR42790:SF3; KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          33..415
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
FT   REGION          179..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..209
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   425 AA;  47432 MW;  1E728C8A43F92D54 CRC64;
     MNYARFLTAV SASRTSSPIR AVTGKLIKAP KSVISLATGA PNPSLFPFKA AAITVEDGTT
     IQFGEEMMEK ALQYSQSAGI PELLSWLKQF QVRLHNPPTV HYPPSQGQMD ICVTSGSQDG
     LCKVFEMILN PGDNVLLNEP IYGGTLQALK PLGCNMISVA SDQHGMIPGS LREILSKWKP
     EDSKNPEKNT PKFLYTVPNG DNPTGNSLTS DRKKQIYELA RKYDFLIVED DPYYFLQFNE
     TWAPTFLSMD VDGRVIRADS FSKVLSSGLR VGFLTGPKPL IERVVFHTEA SSVHASTFNQ
     FMVSQLLHRW GEEGFLAHVR RVIDFYRNQK DAVLAAADKW LNGLAEWHAP TAGMFLWIKI
     KGISDVKELL EEEALKREIL LLPGNCFYFD SSAPCPYLRV SFSLPSPEQM DTAFKILAQL
     IRESL
//