ID H0XV09_OTOGA Unreviewed; 389 AA.
AC H0XV09;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000019951.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000019951.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQR03116311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03116312; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XV09; -.
DR STRING; 30611.ENSOGAP00000019951; -.
DR Ensembl; ENSOGAT00000025505.1; ENSOGAP00000019951.1; ENSOGAG00000026578.1.
DR eggNOG; ENOG502QUS8; Eukaryota.
DR GeneTree; ENSGT00940000153309; -.
DR HOGENOM; CLU_012560_8_1_1; -.
DR InParanoid; H0XV09; -.
DR OMA; EITTYCH; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF349; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 79..378
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 76..117
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 283..342
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 389 AA; 43554 MW; 835A9B8C98A6B7B0 CRC64;
FTTHSTTFSS NYRSLGSVQA PSCSVWPTSS AASVYAGAGD LGSQISMSCS TSFQGGWGSG
GLAMGMARGL TGIGGIQTKK ETMQELNDRL ASYLDRVRNL ETDNRRLESK IWEHLEKKGP
QVRDWAHYFK TIKDLRAQIF AYSVDNALIV LQIDNARLAA DDFRVKYETE LAVRQSVERD
IHGLRKVIDT NITPLQLESE IEALKEELLS MKKNHEEEIA SSGLTVEVDA PTSQDLSKIM
ADMWAQYDEL PQKNQESLAK TTEESTSVVT SQFSEVRAAK TMLTELTCTV KSLEIELDSM
RNQKSRLEDS LREVEAHYAM QMEQLNGVLL HLESELAQIK LDSMRNQKEY EALLNIKVKL
EAEITTYCHL LKDGEDFNLG DALDSSNSM
//
