ID H0XX77_OTOGA Unreviewed; 311 AA.
AC H0XX77;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Leucine rich repeat containing 55 {ECO:0000313|Ensembl:ENSOGAP00000020720.1};
GN Name=LRRC55 {ECO:0000313|Ensembl:ENSOGAP00000020720.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000020720.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000020720.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03172118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XX77; -.
DR STRING; 30611.ENSOGAP00000020720; -.
DR Ensembl; ENSOGAT00000002477.2; ENSOGAP00000020720.1; ENSOGAG00000002476.2.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000161412; -.
DR HOGENOM; CLU_000288_18_10_1; -.
DR InParanoid; H0XX77; -.
DR OMA; WSQLPWP; -.
DR TreeFam; TF334689; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR GO; GO:0099104; F:potassium channel activator activity; IEA:Ensembl.
DR GO; GO:0044325; F:transmembrane transporter binding; IEA:Ensembl.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR46473; GH08155P; 1.
DR PANTHER; PTHR46473:SF5; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..47
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 48..311
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003545830"
FT TRANSMEM 271..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..82
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 209..263
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 311 AA; 34306 MW; B5148DEAB7B5ED1D CRC64;
MGSLQHCCCQ LPKMGDTWAQ LPWPGPPHPA MLLISLLLVS GLMPSEAGSS CPVLCTCRNQ
VVDCSSQRLF SVPPDLPMDT RNLSLAHNRI AAVPPGYLTC YMELRVLDLR NNSLIELPPG
LFLHAKRLAH LDLSYNNLSH VPADMFQEAH GLVRIDLSHN PWLRRVHPQA FQGLVQLRDL
DLSFGGLAFL SLEALEGLPG LVTLQIGGNP WVCGCTMEPL LKWLRNRIQR CTADSQLAEC
RGPPEVEGAP LFSLTEESFK ACHLTLSLDD YLFIAFVGFV VSIASVATNF LLGITANCCH
RWSKASEEEE I
//
