ID H0Y1Q4_OTOGA Unreviewed; 1937 AA.
AC H0Y1Q4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000022297.1};
GN Name=LOC100954756 {ECO:0000313|Ensembl:ENSOGAP00000022297.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000022297.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000022297.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; AAQR03148784; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03148785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03148786; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03148787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03148788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 30611.ENSOGAP00000022297; -.
DR Ensembl; ENSOGAT00000030059.1; ENSOGAP00000022297.1; ENSOGAG00000028575.1.
DR eggNOG; KOG0161; Eukaryota.
DR GeneTree; ENSGT00940000160705; -.
DR HOGENOM; CLU_000192_8_0_1; -.
DR InParanoid; H0Y1Q4; -.
DR OMA; NMEQCQN; -.
DR TreeFam; TF314375; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 30..79
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 83..779
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 657..679
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 844..1306
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1332..1925
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1937 AA; 223444 MW; 4122A87AF8204731 CRC64;
KGECGDDVDP MPFLAPPDKE RIEAMNKPYD IKRSCWVKDE KEGFIAGEIQ SEQGDQVTVK
TVTNQTLTMK KDDIQQMNPP KFYQANDMAD MTFLNEASVL DNLRQRYVNM RIYTYSGLFC
VTVNPYRWLP IYGARVANMY KGKKRTEMPP HLFSISDNAY HDMLMDRENQ SMLITGESGA
GKTENTKKVI QYFANIGGTG KQSSDKKPPG GQGSLEDQII QANPVLEAFG NAKTTRNNNS
SRFGKFIRIH FGTTGKLAGA DIESYLLEKS RVISQQAAER GYHIFYQILS NKKPELVESL
LLVPNPKQYH WVSQGVTMVE NMDDGEELQI TDDAFDVLGF SAEEKMGVYK LTGGIMHFGN
MKFKQKPREE QAEVDTTEVA DKVAHLMGLN SGELQKGITR PRVKVGNEFV QKGQNMEQCQ
NSIGALGKAV YDKMFKWLVV RINKTLDTKM QRQFFIGVLD IAGFEIFEFN SFEQLCINFT
NEKLQQFFNH HMFVLEQEEY KREGIEWVFI DFGLDLQACI DLLEKPMGIF SILEEQCVFP
KATDATFKAA LYDNHLGKSS NFLKPKGSKG KGPEAHFELI HYAGTVGYNI TGWLEKNKDP
LNETVVGLFQ KSTLGLLGLL FKEEEAPGIA DSMSSGTKKQ KRGSSFMTVS NFYREQLNKL
MATLHSTAPH FVRCIVPNEF KQSGVVDAHL IMHQLACNGV LEGIRICRKG FPNRLQYPEF
KQRYQVLNPN VIPQGFVDNK KASELLLGSI DLDTNEYKIG HTKVFFRAGI LAKLEDMRDE
RLAKIMTMLQ CRLRGFLMRV EFKKMLERSR IGLKVIQRNV RKFLQLRFWG WWKLYNKVKP
LLNVARQEEE MKVKEEELRS AMAKTQELIN KVKELEEKMA TLSQEKKDLT IQLQAEQENL
MDAEERLTQM MKTKMELESQ IADMRERLEE EEGMAASLSA AKRKLEGELS DLKRDLEGLE
TTLAKTEKEK QALDHKVRTL TGDLSLREDS IAKLQKEKRA LEELHQKTLD DLQAEEDKVN
HLTKNNSKLS TQIHELEDNW EQEKKIRAEV EKARRKAEGD LKMTIDNLNE MERSKLDLEE
VVKKRDMEIN SINSKYEDEQ SLNSTLQRKL KEYQARIEEL EEELEAERAM RAKVEKQRSD
LARDLEDLSD RLEEAGGATS AQIEQNRKRE AELLKLRREL EEAALQSEAT ASTLRKKHTD
SMAELTEHVE SLQRIKSKLE KDKQVMKAEI EDLNASVETI QKSKLNAEAH VRKLEDNLSE
ANAKVAELER NQAEINAIRT RLQAENSELS REYEESQSRL NQLLRIKTSL TSQTDDYKRQ
LDEESKSRSA AVVSLANTKH DLDLLKEQLE EEQGGKSELQ RLVSKLNTEV TSWRTKYETD
AIQRTEELEE TKRKLAARLQ EAEEAAEAAQ ARAASLEKNK QRLQAEVEDL TIDLEKANAA
AAALDKKQRV FDKMLAEWQQ KCEELQVEVD SSQKECRMYM TESFKIKTAY EEVLEHLESA
KKENKTLQEE IKDLIDQLGE GGRSVHELQK LKKKLEIEKE ELQVALEEAE SSLEVEESKV
IRIQLELAQV KADIDRRIHE KEEEFEATRK NHQRAIESLQ ASLEAEAKGR AEALRLKKKM
ETDLNEMEIQ LDHANKNNSE LVKTLKRLQQ QIKDLQVQMD EDARQHEELR EQYNLQERRL
SLLQTELEEV RSALEGSERS RKLLEQEVVE ITERHNEVNI QNQSLLVVKR KLESDVQRIS
NEHEELISEF RSADERAKKA MTDAARMAEE LRQEQDHCMH LEKIKKNYEV TIKDLQAKME
EAEQLALKGG KRTIMKLEAR IKELETELDG EQKQHAESVK TLRKNERRVK ELVFQTEEDH
KTNQRMQELV EKLQNKLKVY KRQMEEAEEQ ANQTLARYRK TVHELDDAEE RAGMAETALN
KLRTRHRVAG KGITSVE
//
