ID H0YPB5_TAEGU Unreviewed; 359 AA.
AC H0YPB5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=N-acetylneuraminate synthase {ECO:0000313|Ensembl:ENSTGUP00000000112.1};
GN Name=NANS {ECO:0000313|Ensembl:ENSTGUP00000000112.1};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000000112.1, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000000112.1, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000000112.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002186957.1; XM_002186921.3.
DR AlphaFoldDB; H0YPB5; -.
DR STRING; 59729.ENSTGUP00000000112; -.
DR Ensembl; ENSTGUT00000000114.2; ENSTGUP00000000112.1; ENSTGUG00000000113.2.
DR GeneID; 100227675; -.
DR KEGG; tgu:100227675; -.
DR CTD; 54187; -.
DR GeneTree; ENSGT00390000011081; -.
DR HOGENOM; CLU_040465_1_0_1; -.
DR InParanoid; H0YPB5; -.
DR OMA; MTYIDYR; -.
DR OrthoDB; 3716025at2759; -.
DR TreeFam; TF324826; -.
DR Proteomes; UP000007754; Chromosome Z.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 294..353
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 359 AA; 40149 MW; 606855C4FCFBD196 CRC64;
MAGEFELCPG RRVGGDQPCF IIAEIGQNHQ GDLEIAKRMI RMVKECGADC AKFQKSELEY
KFNKKALERP YTSKHSWGKT YGEHKRHLEF SHDQYRELKK YAEEIGIFFT ASGMDEMAVE
FLHELDVPFF KVGSGDTNNF PYLEKTAKKG RPMVISSGMQ SMNTMHQVYQ IVKPINPNFC
FLQCTSAYPL QPEDVNLRVI SAYQSAFPDI PIGYSGHETG IAISVAAVAM GAKVLERHVT
LDKTWKGSDH QASLEPNELA ELVKAIRTVE KAMGSPIKQL LPCEMACNEK LGKSVVAKVA
IPEGTVLTLD MLTVKVGEPK GFPPECIFDL VGQKVKKNIE EDETITEQVV ENHVKKVKC
//
