ID H0YQI3_TAEGU Unreviewed; 1527 AA.
AC H0YQI3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=ERCC excision repair 6 like 2 {ECO:0000313|Ensembl:ENSTGUP00000000540.2};
GN Name=ERCC6L2 {ECO:0000313|Ensembl:ENSTGUP00000000540.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000000540.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000000540.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000000540.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 59729.ENSTGUP00000000540; -.
DR Ensembl; ENSTGUT00000000548.2; ENSTGUP00000000540.2; ENSTGUG00000000524.2.
DR GeneTree; ENSGT00940000161328; -.
DR HOGENOM; CLU_000315_17_10_1; -.
DR InParanoid; H0YQI3; -.
DR OMA; PDSEPCH; -.
DR OrthoDB; 5399336at2759; -.
DR TreeFam; TF351516; -.
DR Proteomes; UP000007754; Chromosome Z.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18005; DEXHc_ERCC6L2; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR CDD; cd20400; Tudor_ERCC6L2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR029256; Heliccase-ass-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF14773; VIGSSK; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 127..312
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 503..660
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 712..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1008..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1277..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1438..1465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1042
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1299..1321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1438..1453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1527 AA; 174386 MW; B94B65F50749783D CRC64;
MCDDGVPDHW HIGEKCFAPC FENGKLHEGT ITSLEKDKNG KSFAVVSFLD SEERKILIRK
LCKIKDSRGP WKSSIFDEGD LEKPYFPDQN LPSPGVAFKL SDNGDFIPYT INRYLRDYQR
EGAQFLYRHY ANKRGCILGD DMGLGKTIQV ISFLAAVLHK KGTREDIENN MPEFLLRTMK
KGSDCNPKKT FLIVAPLSVL YNWKDELDTW GYFKVSVLHG SKKDDDMNRI KQGKCEVALT
TYEILRLYLD EFNSIEWSAV IVDEAHRIKN PKAQITQTMK SLKCSVRIGL TGTILQNNMK
ELWCVMDWAV PGLLGSRVHF KKKFSDPVEH GQRHTATKRE LATGRKAMVK LARIMSGWFL
RRTKALISDQ LPKKEDRMVF CSLTEFQKAV YQAVLETDDV TLVLRAGEPC SCNSGQKRKN
CCYKANAHGE TIKSLRFSYL MILQKVANHA ALLQTDNTSK LQEVHIKRVC SQVFSSFPDF
VQLSKDAAFE TISDPKYSGK MKVLQQLLNH FQKNKDKVLL FSFSTKLLDV LEQYCMASGL
DYRRLDGNTK SEDRIRIVRE FNSLQEINIC LVSTMAGGLG LNFVGANVVI LFDPTWNPAN
DLQAIDRAYR IGQHRAVKVF RLISLGTVEE IMYLRQVYKQ QLHCAVIGTE NARRYFEAVQ
GSKEHQGELF GIHNLFKLRT HGSCLTKDIL EREGRVEAGV MTATTWLKEE NRSCSSEEYE
EPDCQEDGDP QSVRAQLKRE ETEFWDDLSD DDVLESSVKK SDRRKPCNEN SFVVTKGQLS
LIQCGFSKLL QREIKTTKEG DHNYNSHHSS SNDHTIRKNV NSKHGGFQNC QTVVPVLEHG
KAVLSPNGSD KQDMHSSTEW LGLSGSEEEG DRENEDQSIL KQCDIVMETE SSSEADDDVI
FPTQVQVCQQ PVLTKEDEMH RSTSENCEEL AKEKAGFVFK GNSRQFGFHS AESDCTIPIE
DVKNDIDLKG ASDISDESDD IELPYNSESR KLGTRRFPKW KESLPQVKKP YRKGEESRSQ
NIDEFSSSEE SSPIEKMHAR KQSNRSKQQS SRIQFGSKML CPIQDTSVAQ MKSKNYAVRR
TYASKTVFEH QEKNMESMDK YLDGVQEVAY IHSNQNVVGS SKAENHLSRW AVHDVFELKQ
FSQLPANVAV CSAKKNFEVP EDSTSEKKIV KERQEMLKNR KQHHLHVTHP VTQRSKKVHR
VGSATFMIGR TPKEIRRRQF EEMVSHFNMG SVKDLAEHIA KATSETRQKL LKEFYVSKHP
EIESFFSLEI PAEASHNCEE RELGTTRSRK RKSFVNFRRS ESRPSSAKGL LLSGTTETQT
QESHKGETEQ LHKDSYLQHM FVDAKYKQSP TVAPRHIQRR NSQAFKDFMA SGSLSSKSEI
IEVLPTKSCG GQQNSEETQL PKERSVSQSE NGDRKAQICK KNSFVDLLGD TSILDEIFRN
DGNGSTGSPR RFSSRQAEKS KGRPKDFWDM LNEQNEDSLR KLTDIAVIEK LCERAPHSSV
TEEREVCESS LWKRNETFLW KKYRADD
//
