ID H0YQS3_TAEGU Unreviewed; 753 AA.
AC H0YQS3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=SRY-box transcription factor 30 {ECO:0000313|Ensembl:ENSTGUP00000000630.2};
GN Name=SOX30 {ECO:0000313|Ensembl:ENSTGUP00000000630.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000000630.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000000630.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000000630.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0YQS3; -.
DR STRING; 59729.ENSTGUP00000000630; -.
DR Ensembl; ENSTGUT00000000641.2; ENSTGUP00000000630.2; ENSTGUG00000000620.2.
DR GeneTree; ENSGT00940000161042; -.
DR HOGENOM; CLU_562104_0_0_1; -.
DR InParanoid; H0YQS3; -.
DR OMA; FIPSPAY; -.
DR TreeFam; TF336594; -.
DR Proteomes; UP000007754; Chromosome 13.
DR GO; GO:0010369; C:chromocenter; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0120211; P:proacrosomal vesicle fusion; IEA:Ensembl.
DR GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR CDD; cd22033; HMG-box_SoxH_SOX30; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR47279; TRANSCRIPTION FACTOR SOX-30; 1.
DR PANTHER; PTHR47279:SF1; TRANSCRIPTION FACTOR SOX-30; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 351..419
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 351..419
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 81341 MW; D7DE17E6A6C58591 CRC64;
MNAEGREVPH RQRLQTPVHI PAEPLLSLPS TPKALAPFPS PDHSLPPGSE AAGESKIPVE
FRALERPSGG HEISDPAPAG LTGRAGTAQR NPGTTRTPLL GPHLWKLRPS SRTTIQQLGR
TVSSASKSRT YSNLLLAMAR PRRPRGEPGA QPAAMAAAAR QQRSMAGAEA EGAAPGPSGR
PGAALGGAGG RSAGRFRHRP PWRLRGAEPG PAARAPRSER AEQRARDGRS GRPQRWARDG
TARWSRRGCV KVDKIDAPSG SLCEPGNAPQ DQNIPVLFQS LPPMSHVQLQ GPLPSQQMHG
TPVPVKQVAV QLQPLHLQRP KIETKNVPLT VLPSDSGMPD TPFSKTKSGR VKRPMNAFMV
WARIHRPAVA KANPGANNAE ISVQLGLEWS KLTEEQKQPY YEEANKIKLR HREEFPGWVY
QPDRKKGSLP PRSAAFLGTS QSTITTNPAG TLPFSSPTYS FVNSSGKNST GRESPAIRLT
ASSIQHTMPM TLFQTTAAST TSVAVAVPTL PLRPVVSSQH FAGPAQTEAF VSPGLNFSLK
RPAPIFAESF GNRNPSNISS TSGRFSVSNS EIPGIPVFPR GIALPQATPF IPSPAYVSAP
IGQPAGLFGG TPQFPCCQPS FIPGPRCFPS STFPLRAPFG YGNFSSSVPQ CFGFYEERNQ
RQEVIFSTVD EDYHFRAYSE ERLCENQRVC RNPEIVSCQS TCGEERVLSP LPQLDVEVVE
EVLPSPPSSP SSTYIVNVTD SDEEEEVKFF QVL
//
