ID H0YU37_TAEGU Unreviewed; 1408 AA.
AC H0YU37;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Cytoplasmic linker associated protein 2 {ECO:0000313|Ensembl:ENSTGUP00000001805.2};
GN Name=CLASP2 {ECO:0000313|Ensembl:ENSTGUP00000001805.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000001805.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000001805.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000001805.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 59729.ENSTGUP00000001805; -.
DR Ensembl; ENSTGUT00000001822.2; ENSTGUP00000001805.2; ENSTGUG00000001731.2.
DR GeneTree; ENSGT00940000155574; -.
DR HOGENOM; CLU_005060_0_0_1; -.
DR InParanoid; H0YU37; -.
DR OMA; FDDGHIS; -.
DR TreeFam; TF101155; -.
DR Proteomes; UP000007754; Chromosome 2.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF30; CLIP-ASSOCIATING PROTEIN 2; 1.
DR Pfam; PF21040; CEP104-like_TOG; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 1.
DR SMART; SM01349; TOG; 3.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 218..451
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 745..999
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 1164..1397
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 143..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 992..1042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1174..1205
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 448..477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1408 AA; 154251 MW; 62BE5446122FA054 CRC64;
MGDAKDQVRE QAQNLILKLM CEAAPPMYIW ERLAVGFKHK NYRSREGVCL CLVATLNIYG
AQPLILSKLV PHLCVAFGDS NSQVRDAAIL AIVEVYRHVG EKVRIDLAKR GIPPGRLQTI
FSKFDEIRNS DNMILSNISD KSFDDEESVD GNRPSSAASA FKVPAPKKPG NPSNSARKPG
SAGGPKVGGS SKEGGAGAVD EDDFIKAFTD VPTVQIYSSR ELEETLNKIR EILSDDKHDW
DQRTNALKKV RSLLVAGAAQ YDGFFQHLRL LDGAFKLSAK DLRSQVVREA CITVAHLSTV
LGNKFDHGAE AIVPTLFNLV PNSAKVMATS GCAAIRFIIR HTHVPRLIPL ITSNCTSKSV
AVRRRSFEFL DLLLQEWQTH SLERHAAVLV ETIKKGIHDA DAEARVEARK AYLGLRNHFP
SEAETLYNSL EPPYQRSLQT YLKNSGSIAS LPQSDRSSSS SQESLNRPLS SKWSAASPAS
LAGRVPGSSK GVPSPGTLQR SRSDIDVNAA AGAKARHAAG QTAGAGRLSA AGLPPGSYAS
LGRIRSKLST PSVGIGSSKT DSRGRSRTKM VSQSQPGSRS GSPGRVLTTT TLSTMNTGVQ
RVLVNPASAQ KRSKIPRSQG CSREASPSRL SVARGSRIPR PSVSQGCSRE ASRESSRDTS
PVRSFPPLGT GFGISQSSRL SSSVSAMRVL NTGSDVEEAV ADALKKPVRR RYESYGMYSD
DDANSDASSA CSERSYSSRN GSIPTYMRQT EDVAEVLNRC ASTNWSERKE GLLGLQNLLK
NQRTLSRVEL KRLCEIFTRM FADPHSKVFS MFLETLVDFI QVHKEDLQDW LFVLLTQLLK
KMGADLLGSV QAKVQKALDV TRESFPNDLQ FSILMRFTVD QTQTPSLKTV KPALQDQLRS
FWSSKVKVAI LKYIETLAQQ MDPGDFVNSS ETRLAVSRII TWTTEPKSSD VRKAAQSVLI
SLFELNTPEF TMLLGALPKT FQDGATKLLH NHLRNTGNSG QGSMGSPLTR PTPRSPASWS
SPLTSPTNTS QNTLSPSAFD YDTENMNSED IYSSLRGVTE AIQNFSFRSQ EDMNEPVKRD
AKKDDGDSIC SASGIMEMRA GSGVSETGRT ALDNKTSLLN TMPPHSSPRS RDYNPYNYSD
GISAFNKSAL KEAMFDDDAE QFPDEPPMDH SDLVAELLKE LSNHNERVEE RKAALYELMK
LTQEESFGVW DEHFKTILLL LLETLGDKEH AIRALALKVL REILRNQPAR FKNYAELTIM
KTLEAHKDPH KEVVRSAEEA ASMLATSISP DQCIKVLCPI IQTADYPINL AAIKMQTKVI
ERVSKETLTQ LLPEIVPGLI QGYDNSESSV RKACVFCLVA IHAVIGDELK PHLSQLTGSK
MKLLNLYIKR AQTGSGAGDT AADMSGQS
//
