ID H0Z3P4_TAEGU Unreviewed; 617 AA.
AC H0Z3P4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Matrilin 4 {ECO:0000313|Ensembl:ENSTGUP00000005188.2};
GN Name=MATN4 {ECO:0000313|Ensembl:ENSTGUP00000005188.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000005188.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000005188.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000005188.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; H0Z3P4; -.
DR STRING; 59729.ENSTGUP00000005188; -.
DR Ensembl; ENSTGUT00000005240.2; ENSTGUP00000005188.2; ENSTGUG00000005029.2.
DR GeneTree; ENSGT00940000157086; -.
DR HOGENOM; CLU_008905_7_0_1; -.
DR InParanoid; H0Z3P4; -.
DR OMA; DKRSCSM; -.
DR TreeFam; TF330078; -.
DR Proteomes; UP000007754; Chromosome 20.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..617
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025607564"
FT DOMAIN 34..213
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 256..296
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 386..561
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 617 AA; 68339 MW; 1E24962EA3D6246D CRC64;
MKLLPVASLF LLLLTTLEAR PKPAALKCRT GPLDIVFVID SSRSVRPFEF ETMRRFMMDI
IGNLDVGPNA TRVGVIQYSS QVQNIFSLKT FFTRADMERA INSIIPLAQG TMTGLAIQYA
MNVAFTTQEG ARPLHKRIPR IAIVVTDGRP QDRVTEVATQ ARNAGIEIYA VGIQRADMNS
LRAMASPPLE EHVFLVESFE LIQQFAKQFQ DKLCGVDMCM GREHGCQHSC VSTPGSFYCE
CNPGYRLNVD GKTCSPIDAC ADGSHGCQHH CVSTRGSYSC RCRPGYYLSH NKRSCTMIDY
CSFGNHSCQH ECVSIPNGHY CRCRSGFTLQ PDSKSCRATD LCNGVDHGCE FKCVSTEGSY
HCVCPEGQQL QADGKTCSKC GAGHVDLVMV IDGSKSVRPQ NFELVKQFVN RIVDLLEVSP
HGTRVGLVQY SSRVRTEFPL NKYHSADEIK KAVMDVEYME KGTMTGLALK HMVEHSFSEL
EGARPLSYNI PRIGLVFTDG RSQDDISEWA RRAKESGIVM FAVGVGKAVE EELRAIASEP
VEQHFSYSAD FTTMTHLVEN FSLNICPEEG KGETEIHSPC ECEALVQFQT NTVAILQSLT
EKNILWGDAW ACQGAEG
//
