ID H0Z6R9_TAEGU Unreviewed; 475 AA.
AC H0Z6R9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=SH2 domain containing 4B {ECO:0000313|Ensembl:ENSTGUP00000006268.2};
GN Name=SH2D4B {ECO:0000313|Ensembl:ENSTGUP00000006268.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000006268.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000006268.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000006268.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0Z6R9; -.
DR STRING; 59729.ENSTGUP00000006268; -.
DR Ensembl; ENSTGUT00000006331.2; ENSTGUP00000006268.2; ENSTGUG00000006102.2.
DR GeneTree; ENSGT00940000159732; -.
DR HOGENOM; CLU_029296_1_0_1; -.
DR InParanoid; H0Z6R9; -.
DR OMA; IKQKFRH; -.
DR TreeFam; TF336893; -.
DR Proteomes; UP000007754; Chromosome 6.
DR CDD; cd10351; SH2_SH2D4B; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035839; SH2D4B_SH2.
DR PANTHER; PTHR14388:SF7; SH2 DOMAIN-CONTAINING PROTEIN 4B; 1.
DR PANTHER; PTHR14388; T CELL-SPECIFIC ADAPTER PROTEIN TSAD; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 369..461
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 192..232
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 247..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 54888 MW; 17B9125A9DBE0A8C CRC64;
MISTCRGSRE AAAPSGQHQP SFPGRFVPAR RAGRPWHGVP ARPGLWACEG RAEGRLRMKS
LEQNRTRGFC RVWRCERSRA RSSGVVQPGR GSVEEKAEPV WKAAAGVACG NGKRVQWLRG
KDGEVWVWVM GEAPGDKPYE QISEELIAER ARQQAQKEAE ELWRQKEAEI TKKFRDAMAQ
EKARIVAEKW KIEMEDRKAA KLEEEKIQEE LKKREEEERQ KGEELIRQQE EIRAKELYLS
LKQAQQHSQH SDDDQEWEEQ LRRSKAADEE RSHKARRARD EYRRQSLRAI QKGRVAGLSH
LFQGTNLSND QEIKPNNSAS PLLPPVTSSS IWERPSRPFS RDVIIRWFKE EQIPRRAGFE
RNTNRIAQWF HGIISRQEAE ELLMNKSEGA FLVRVSEKIW GYALSYRQQN GFKHFLVDAS
GDFYSFLGVD PNRHPTLTDL IDFHKEEIIT SSGGELLLEP CGQQKNPPDY SPLFE
//
