ID H0Z9W5_TAEGU Unreviewed; 480 AA.
AC H0Z9W5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DDB1- and CUL4-associated factor 10 {ECO:0000256|ARBA:ARBA00021765};
DE AltName: Full=WD repeat-containing protein 32 {ECO:0000256|ARBA:ARBA00030914};
GN Name=DCAF10 {ECO:0000313|Ensembl:ENSTGUP00000007368.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000007368.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000007368.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000007368.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May function as a substrate receptor for CUL4-DDB1 E3
CC ubiquitin-protein ligase complex. {ECO:0000256|ARBA:ARBA00002614}.
CC -!- SIMILARITY: Belongs to the WD repeat DCAF10 family.
CC {ECO:0000256|ARBA:ARBA00005903}.
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DR AlphaFoldDB; H0Z9W5; -.
DR Ensembl; ENSTGUT00000007441.2; ENSTGUP00000007368.2; ENSTGUG00000007150.2.
DR GeneTree; ENSGT00390000012666; -.
DR HOGENOM; CLU_028919_2_0_1; -.
DR InParanoid; H0Z9W5; -.
DR OMA; RFLDNRM; -.
DR OrthoDB; 3079463at2759; -.
DR Proteomes; UP000007754; Chromosome Z.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR039085; DCA10.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14588; DDB1- AND CUL4-ASSOCIATED FACTOR 10; 1.
DR PANTHER; PTHR14588:SF2; DDB1- AND CUL4-ASSOCIATED FACTOR 10; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 128..161
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 170..202
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 52358 MW; E5B9E9AFF0D4CABC CRC64;
MSKGPGPEPG PGPGPEPRPE PGPPPLPLRH GDPAAAGPGA PGGLFAWLRG RCLGRGAAVD
PAREAFGAMT GLYGAIQPAD SVCLSTRTHG AVFNLEYSPD GSVLTMACEQ TEVLLFDPIS
SKHIKTLSEA HEDCVNNIRF LDNRLFATCS DDTTIALWDL RKLNTKVCTL HGHTSWVKNI
EYDTNTRLLV TSGFDGNVII WDTNRCTEDG CPHKKFFHTR FLMRMRLTPD CSKMLISTSS
GYLLILHDLD LNKSLEVGSY PILRARRTTS SSDITSSGSS GPRAVGSPCH QNNSGPPSEK
TLSRPSQREG GSPRNSLEVL TPEVPGERDR GNCITSLQLH PKGWATLLRC SSNTDDQEWT
CVYEFQEGAP VRPVSPRCSL RLTHCIEEAN VGRGYIKELC FSPDGRMISS PHGFGIRLLG
FDAQCSELVD CLPREASPLR EIRSLYSHND VVLTTKFSPT HCQIASGCLS GRVSLYQPKF
//
