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Database: UniProt
Entry: H0ZAR3_TAEGU
LinkDB: H0ZAR3_TAEGU
Original site: H0ZAR3_TAEGU 
ID   H0ZAR3_TAEGU            Unreviewed;       778 AA.
AC   H0ZAR3;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   22-NOV-2017, entry version 41.
DE   SubName: Full=Potassium voltage-gated channel subfamily Q member 2 {ECO:0000313|Ensembl:ENSTGUP00000007668};
GN   Name=KCNQ2 {ECO:0000313|Ensembl:ENSTGUP00000007668};
OS   Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea;
OC   Estrildidae; Estrildinae; Taeniopygia.
OX   NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000007668, ECO:0000313|Proteomes:UP000007754};
RN   [1] {ECO:0000313|Ensembl:ENSTGUP00000007668, ECO:0000313|Proteomes:UP000007754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20360741; DOI=10.1038/nature08819;
RA   Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA   Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA   Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA   Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C.,
RA   London S.E., Li Y., Lin Y.C., George J., Sweedler J., Southey B.,
RA   Gunaratne P., Watson M., Nam K., Backstrom N., Smeds L., Nabholz B.,
RA   Itoh Y., Whitney O., Pfenning A.R., Howard J., Volker M.,
RA   Skinner B.M., Griffin D.K., Ye L., McLaren W.M., Flicek P.,
RA   Quesada V., Velasco G., Lopez-Otin C., Puente X.S., Olender T.,
RA   Lancet D., Smit A.F., Hubley R., Konkel M.K., Walker J.A.,
RA   Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z., Eichler E.E.,
RA   Stapley J., Slate J., Ekblom R., Birkhead T., Burke T., Burt D.,
RA   Scharff C., Adam I., Richard H., Sultan M., Soldatov A., Lehrach H.,
RA   Edwards S.V., Yang S.P., Li X., Graves T., Fulton L., Nelson J.,
RA   Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT   "The genome of a songbird.";
RL   Nature 464:757-762(2010).
RN   [2] {ECO:0000313|Ensembl:ENSTGUP00000007668}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTGUP00000007668}.
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DR   EMBL; ABQF01028188; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABQF01028189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABQF01028190; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABQF01028191; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 59729.ENSTGUP00000007668; -.
DR   Ensembl; ENSTGUT00000007747; ENSTGUP00000007668; ENSTGUG00000007434.
DR   eggNOG; KOG1419; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00550000074513; -.
DR   InParanoid; H0ZAR3; -.
DR   OMA; VTVPMYS; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   TreeFam; TF315186; -.
DR   Reactome; R-TGU-1296072; Voltage gated Potassium channels.
DR   Proteomes; UP000007754; Chromosome 20.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR   GO; GO:0030506; F:ankyrin binding; IEA:Ensembl.
DR   GO; GO:0005516; F:calmodulin binding; IEA:Ensembl.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   InterPro; IPR020969; Ankyrin-G_BS.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR003947; K_chnl_volt-dep_KCNQ2.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   PANTHER; PTHR11537:SF6; PTHR11537:SF6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01461; KCNQ2CHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007754};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     25     48       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     69     88       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    153       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    219       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        2    219       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      367    565       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   778 AA;  86368 MW;  75CDF3AF8AB497F0 CRC64;
     FLLVFSCLVL SVFSTIDEYQ NSSEGALYIL EIVTIVVFGV EYFVRIWAAG CCCRYRGWRG
     RLKFARKPFC VIDIMVLIAS IAVLAAGSQG NVFATSALRS LRFLQILRMI RMDRRGGTWK
     LLGSVVYAHS KELITAWYIG FLCLILASFL VYLAEKGENE HFDTYADALW WGLITLTTIG
     YGDKYPQTWN GRLLAATFTL IGVSFFALPA GILGSGFALK VQEQHRQKHF EKRRNPAAGL
     IQAAWRFYAT NLSRTDLHST WQYYERTVTV PMYSTQTQTY GASRLIPPLN QLELLRNLKS
     KSGLTFRKEQ QPEPSPSKSK PCRESLCGCC SGNSSQKVSL KDRVFSSPRG AGTKGKGSPQ
     AQGIRRSPSA DQSIEDSPSK VPKSWSFGDR SRARQAFRIK GAASRQNSEE ASLPGEDIPD
     ENKSCNCEFV TEDLTPGLKV SIRAVCIMRF LVSKRKFKES LRPYDVMDVI EQYSAGHLDM
     LSRIKNLQAR QETPLFASFS TAFFDQIVGR GSSMTDKDRT KGPAEGELPE DPSMMGRLGK
     VEKQVQSMEK KLDFLVNIYM QRMGIPPTET EAYFGSKEPD PAPPYHSPED SREHIDKNGC
     IIKIIRSTSS MGQKNFSAPP APSNACPPST SCQRQSHGSS PIGDPGSLVR IPPPPSHERS
     LSAYSSGHRA SAEYLRNEDI TTKHHESAMR DSDTSISIPS VDHEELERSF SGFSISQSKE
     NLDILNNGCY AAVAKIRPYI AEGESDTDSD LCTPCGPPPR SATGEGPFSD MGWSTPRQ
//
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