ID H0ZHS1_TAEGU Unreviewed; 652 AA.
AC H0ZHS1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=RalA binding protein 1 {ECO:0000313|Ensembl:ENSTGUP00000010137.2};
GN Name=RALBP1 {ECO:0000313|Ensembl:ENSTGUP00000010137.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000010137.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000010137.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000010137.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0ZHS1; -.
DR STRING; 59729.ENSTGUP00000038013; -.
DR Ensembl; ENSTGUT00000010244.2; ENSTGUP00000010137.2; ENSTGUG00000009818.2.
DR GeneTree; ENSGT00940000154639; -.
DR HOGENOM; CLU_028068_1_0_1; -.
DR TreeFam; TF315411; -.
DR Proteomes; UP000007754; Chromosome 2.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd04381; RhoGap_RalBP1; 1.
DR Gene3D; 1.20.58.90; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR039767; RALBP1.
DR InterPro; IPR049041; RalBP1-like_Ral-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR12783; RALA BINDING PROTEIN 1 RALBP1; 1.
DR PANTHER; PTHR12783:SF5; RALA-BINDING PROTEIN 1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF20924; RLIP76_Ral-bd; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 192..380
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..613
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..652
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 75721 MW; BA96C2C92C9F7A7B CRC64;
MTECFLPPTS SPSEHRRVEH SGGLARTPSS EEISPTKFPG LYRTGEPSPP HDSLHEPPDI
VSDDEKEHGK KKGKFKKKEK RTEGYAAFQE DSSGDEAESP SKLKRSKGIH VFKKPSFSKK
KEKDFKIKEK PKDEKHKEEK HKEDKHKEKK SKDLTAADVV KQWKEKKKKK KPIQETEIPQ
VDVPSHRPVF GIPLSDAVDR TMMYDGIRLP AVFRECIDYI EKYGMKCEGI YRVSGIKSKV
DELKAAYDRE ESPNLEEYEP NTVASLLKQY LRELPENLLT KELMPRFEDA CGKSTEAEKV
QECQRLLKEL PECNHLLISW LIVHMDHVIA KELETKMNIQ NISIVLSPTV QISNRVLYVF
FTHVQEFFGN VTLKQVTKPL RWSNMATMPA LPETQESIKE EIRRQEFLLN CLHRDLQAGI
KDLSKEERLW EVQRILTALK RKLREAKRQE CETKIAQEIA SLSKEDVSKE EMNENEEVIN
ILLAQENEIL TEQEELLAME QFLRRQIASE KEEIDRLRAE IAEIQSRQQH GRSETEEYSS
ESESESEDEE ELQVILEDLQ RQNEELENNH LNQAIHEERE AIIELRVQLR LLQRAKSEQQ
GQEEEEPEKR GGVSQQQRDT VLETKAAKEQ PKASKEQQVK PSPSKDRKET PI
//
