ID H0ZNX0_TAEGU Unreviewed; 1548 AA.
AC H0ZNX0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Bromodomain adjacent to zinc finger domain 1A {ECO:0000313|Ensembl:ENSTGUP00000012299.2};
GN Name=BAZ1A {ECO:0000313|Ensembl:ENSTGUP00000012299.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000012299.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000012299.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000012299.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
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DR STRING; 59729.ENSTGUP00000012299; -.
DR Ensembl; ENSTGUT00000012434.2; ENSTGUP00000012299.2; ENSTGUG00000011934.2.
DR GeneTree; ENSGT00940000158135; -.
DR HOGENOM; CLU_002479_1_0_1; -.
DR InParanoid; H0ZNX0; -.
DR OMA; CEATGKD; -.
DR TreeFam; TF316326; -.
DR Proteomes; UP000007754; Chromosome 5.
DR GO; GO:0016590; C:ACF complex; IEA:Ensembl.
DR GO; GO:0008623; C:CHRAC; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:Ensembl.
DR GO; GO:0006334; P:nucleosome assembly; IEA:Ensembl.
DR GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR CDD; cd05504; Bromo_Acf1_like; 1.
DR CDD; cd15627; PHD_BAZ1A; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037325; Acf1_Bromo.
DR InterPro; IPR047171; BAZ1A.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46510; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR PANTHER; PTHR46510:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 22..128
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 412..477
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 1142..1192
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 1145..1190
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1440..1510
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 147..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1272..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1345..1371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1392..1423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 310..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 624..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 148..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1196..1210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1211..1249
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1548 AA; 177780 MW; 74848F9D0A121B6F CRC64;
MPLLHRKPFV RVKPPADLRP DERVFYCRVT NEIFRNYDDF FERTILCNSL VWSCAVTGKP
GLTYQEALES EKRARHNLQS FPEALIIPVL YLATLTHRTR LHEICDEIFA YVKDRYFVDE
TVEVLRNNGA RLQCKVLEVI APAHHNGMAN GHTSSADGDT IVISDSDDSE THNSSAQNGE
KKAIIDPSLF KYKVQPIKKH LYEAVIVKAS QLSRRKHLFS RDRLKLFLKQ HCEPHDGVIK
AKATSIEKYN LAEQNFSCFF PDEPPTFIFS PASRRRGRPP KRASASLSIY QLKLTFYKRK
NNLGLSFSFI AFEKAKLKQE KANAIEARKK EKEDKEKKRE ELKKIVEEER MKKKEEKERL
KIEKEKEREK LREEKRKYVE YLKQWSKPRE DMECDDLKEL PIPMPVKTRL PPEIFGDALM
VLEFLHAFGE LFDLQDEFPE GVTLEVLEEA LVGNDTEGPL CELLFFFLTA IFQAMAEEEE
EVAKDQIADA ETKDLTEALD EDADPTKSAL SAVATLAAAW PQLHQGCNLK NLDLDSCTLS
EILRLHILAS GADITSANAK YRYQKRGGFD TTDDACMELR LSNPGLLKKL SSTSVYDLLP
GEKMKILHAL CGKLLTLVST RDFIEDSVDV LRQAKQEFRE LKAEQHRKER EAAAARIRKK
REERLKEQEL KMKEKQEKLK EEEQRIPAVE IPVGEEERED LDTSTESKEI ERKEQDMDTV
TEDEEELGPN KKRQRGRRRQ NGFKEFTRHE ETTCEKHEPL TAEDEEALKQ EQQKKEKDLL
EKIQNATACT NITPLGRDRL YRRYWIFPSV PGLFVEEDYS GLTEDMLLPR TSSFQNSGQS
CTNEPQVFSK TGESLKSSES TSNIDQDSHT SVVIEVPRPV YKPNRWCFYS SREQLDQLLE
ALNSRGHRES ALKETLLQEK SRIYEQLSSF PVEKFHIPEK PQSDVRPPIG RGRMQNVHDG
SHLSAEKQLE LRLRDFLLDI EDRIYQGTLG AIKVTDRQAW RAALEHGRYE FLNDENKENG
IIKTVNEESE EMETDDHDKF IVKDRLVGLK TEAPSAASTS TSTPQPVSNV VHYLASALLQ
IEQGIERRFL KAPLDASDGG RSYKTVLDRW RESLLSSTSL SQVFLHLSTL DRSVIWSKSI
LNARCKVCRK KGDAESMVLC DGCDRGYHTY CIRPKLKAIP EGDWFCPECR PKQRSRRLSS
RQRPSVESDE ETAEQLEGEE EANYDELGQS EEEHYEEEQD EEDESQEEEE ISLSKQGRSQ
VKFPLKMRAA KLNNPFSSQN SQRQARYASR SQQIESSSKI TRRGLRNIKS ASSAVTKPTL
RLNSRTTRQS QSSLQADVFV ELLSPRRRRR GRKSADKTLG NNPSNSLGFR IVDTADPGEQ
LRKFPVSASK LSLPVAEPKR RGRKRQSTES SPPVLNRRSS GRQGGVHELS AFEQLIVELV
RHDDSWPFMK LVSKIQVPDY YDIIKKPIAL NIIREKVNKC EYKLASEFIE DIELMFSNCF
EYNPRNTSEA KAGTRLQAFF HIQAQKLGLP ITSGNVDHTT PAAKKSRI
//
