ID H0ZPP0_TAEGU Unreviewed; 1191 AA.
AC H0ZPP0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Plakophilin 4 {ECO:0000313|Ensembl:ENSTGUP00000012572.2};
GN Name=PKP4 {ECO:0000313|Ensembl:ENSTGUP00000012572.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000012572.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000012572.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000012572.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR AlphaFoldDB; H0ZPP0; -.
DR STRING; 59729.ENSTGUP00000019080; -.
DR Ensembl; ENSTGUT00000012711.2; ENSTGUP00000012572.2; ENSTGUG00000012202.2.
DR GeneTree; ENSGT00940000155773; -.
DR HOGENOM; CLU_007897_0_0_1; -.
DR TreeFam; TF321877; -.
DR Proteomes; UP000007754; Chromosome 7.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF8; PLAKOPHILIN-4; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 3.
DR SMART; SM00185; ARM; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT REPEAT 568..603
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 612..655
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 870..907
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 131215 MW; B439FF128FCAFAB3 CRC64;
MPAPEQSPMV EEGLPQTAQE TSTGPGMEPE TTATTILASV KEQELQFQRL TRELEVERQI
VANQLERCRL GAESPSIAST SSTEKSFPWR SSDPPPTSVS KPQVSEGVHT NAFDIRTEAE
QGTLYSPEQT SLHERSIGNS RSSTQMNSYS DSGYQEISSF HNSQNLNKSE IRQQHSLGGP
LNNLDVVRSS RAEGQTSVQP SANTATNRVM RRVSSVPSRA QSPSYMVSTS MSPSRGSLRT
SLGSGYGSPS VAEQRSLPSH AYSSTTLPVQ RAGSPYAAHR PASPSAVRRV GSLTSRHANP
GSGAAPYQSA GRVGSPLALA DAQARVTSPS QTQLGSSSPK RSGMTAVPQH LGTTLQRTIH
DMEQYGQQYD IYERMVPPRP DSLTGLRSSY ASQHSQLGQE LRSAVSPDMH ITPIYEGRTF
YSPVYRSPNH GTIELHHGSQ AALFRTGSGM GNLQRSSSQR STLTYQRNTY GLPTAAALAE
PLRAVPFRLP EPGYGRLHPA PDGGTTRSPS IDSIHKDPRE FAWRDPELPE VIHMLQHQFP
SVQANAAAYL QHLCFGDNKV KTEVCRLGGI KHLVDLLDHR VLEVQKNACG ALRNLVYGKS
TDENKIAMKN VGGIPALLRL LRKSVDAEVK ELVTGVLWNL SSCDAVKMTI IRDALSTLTN
TVIVPHSGWN SSSFDDDHKI KFQTSLVLRN TTGCLRNLSS AGEEARKQMR SCEGLVDSLL
YVIHTCVNTS DYDSKTVENC VCTLRNLSYR LELEVPQARL LGINELDDLL GKESPSKDSE
PSCWGKKKKK KKKTSQEDQW DGVGPIPGFS KSPKGVEMLW HPSVVKPYLT LLAESSNPAT
LEGSAGSLQN LSAGNWKFAA YIRAAVRKEK GLPILVELLR MDNDRVVSSV ATALRNMALD
VRNKELIGKY AMRDLVNRLP GGNGPSILSD ETVAAICCAL HEVTSKNMEN AKALADTGGI
EKLVNITKGR GDRSSLKVVK AAAQVLNTLW QYRDLRSIYK KDGWNQSHFI TPVSTLERER
FKSHPSLSTA NQQMSPVMQS VGSTSSSPAL LGIREPRSEY DRTHPSMQYY SSQGDVIAHK
DIYTGSSKAS PIYISSYSSP AREQSRRLQH QQLYYSQEDS TRKNYDAYRL YLQSPHSYED
PYFDDRVHFP ATSDYTPQYG LKSTTNYVDF YSTRRSSYRA EQYPGSPDSW V
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