ID H1A444_TAEGU Unreviewed; 3093 AA.
AC H1A444;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Centrosomal protein 350 {ECO:0000313|Ensembl:ENSTGUP00000017659.2};
GN Name=CEP350 {ECO:0000313|Ensembl:ENSTGUP00000017659.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000017659.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000017659.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000017659.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 59729.ENSTGUP00000030302; -.
DR Ensembl; ENSTGUT00000018062.2; ENSTGUP00000017659.2; ENSTGUG00000017377.2.
DR GeneTree; ENSGT00940000155130; -.
DR HOGENOM; CLU_000421_0_0_1; -.
DR TreeFam; TF329845; -.
DR Proteomes; UP000007754; Chromosome 8.
DR GO; GO:0005813; C:centrosome; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR028750; CEP350/CC187.
DR InterPro; IPR025486; DUF4378.
DR PANTHER; PTHR13958:SF3; CAP-GLY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13958; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14309; DUF4378; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 2479..2521
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1458..1632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1754..1832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1873..2013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2029..2048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2071..2192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2233..2271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2284..2423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2553..2607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2862..2889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1355..1382
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 72..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1075..1111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1187..1201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1516..1534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1572..1619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1754..1771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1772..1806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1807..1832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1873..1889
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1891..1908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1927..2009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2072..2086
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2097..2125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2166..2184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2308..2323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2325..2348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2369..2408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2553..2570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2571..2590
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3093 AA; 344869 MW; 6813B481488521E7 CRC64;
MWSNKSNEVP LQNLRHNQSK DSTRELTAAW ASFSQTKAAL RHIENKLEIA PTSTAVFDSV
MDAKKPSASA SRKSSRKGSR SSSQNKSSKE KSSRSPLRAT TLESNVKKCS RVEFREPLAS
YSSSQLEAKQ LLSSLELSEA EGKSELPACL AHERDERDRH SRGFASPFPS AADGTVVRYL
NDQPTINALQ SNEAFPRAAA LSRLEEEKSS GSRGDESSTR ASQSITSQDS ELKASSSSAT
SICSAHRLEI LKQRQHNAKL EKLKERIRKQ WEHSEELSGR GQHLGYAEQP VVVTNMENTV
TPKVRKVTAV PAAPSYRGFN PAETRIRTPD GKIWRADEFR ISRELYRDIA LQLKEDSTVK
GKSSERNKEK KATRPVRKVQ KLTSPESKQG GNYVISASSW REGQKLAKKI LGPAPRIEQD
RRAVSSDRTG RERAAKSAGC IGRTGSDSRL DVTRKSSSRS SERSRSKVRS ETNLRKLEAA
LPDDNQEDHS SVNKDFLPVE IRGILDDLQL DSMSTKQETD VEKQNQKSVL PTQNMRSHSP
TKRKPDKVAA SEEPQVISKK RHYDSDEVRQ YIIRQQEERK KKQNEEKKAQ KEATEQKNKR
LQELYRKQKE AVTKVKPPPE PSAAKRLQET YSKLLLERTL LEEPPQLPTV QETQPRPGYQ
PSGESDKENK AQERPPSASS SSDMSLSEPP LPLLRSDLME PPWVQPDRLS PRVQLPHPQA
LLGSGGGPCS QHWSLEQMDL LSKECDAMLA GRRSHSAPVG SLMSQLYLNS SAAQENLLVK
PSASQYKSKL DRLEALKATA ASLSSRIETE AKKLAGAGIN YGTTWNSEFI QENQDEGRWA
KAVSPPVREE NENTFSARIQ RMLDACVSHT AFDDSLPGVG NLSEFKKLPE TIRPLTDVIS
LGLRSPAAHR HEGILGHLSK RQMDSPGREN QAYPLSKAVT PHESSIDSIS EGPLLSDENL
SEEEGGQHKQ LPLKMLETLK EKDFCIRERN AFEPIKEFQK AAERYSPLFT QTSDTHSKGP
WEELAKGSPH SVINIFAKNY QLHGKVFEDR LNGGSALLRP LLPAMSPPES VASYEDDFAS
SQGSSTLTDK KISRDLSVGG SSNSSIQEEI PSGKSALEPR SVELGSQHSS GPRSAASSRS
SASSRKRGKK ERLDTFNGSS HHFSVEEDKI LSELERGSQQ AKKSLLSSRI SHKEHEQNPD
TDSTLENLSG HSLMSFSDKG RPQKTPTSSP SSGSQKMLQL DSVGNTAERV KSPSGFSGGT
APGLKPNVAF PDVGLGTSRA AAASASGCMR FSPAGLQHRL SAELNYLSAI EESVRQLSDL
ERVRGISLAQ QESVSLAQIL KAQQQRHERD LALWKIKAEQ EALESQRQLE EARQKAAQVH
AESLQQLVQS RQEAGQEPPC MAAAKQAEPA LLSPGAAHQL REMTELARDT VSAPAAPVSS
LFDHQRQHHS EFMKQLRARA DTNRKCESGA ISQGKDETGD SKQAYSPMFD SYSESSRSKV
HDQSSTSSRQ ESPSVPSSKE NEKKLSHREK TASSIEEQAQ TAADDSLPSD SVLSLPDEKD
SASVATEYSL KFDESMTEDE IEEKSFRSLL PSESHRRNNL EKKRGSRDDS DEEVSPDKTA
LSSIKELSMP FSGGQDSFSK FTMEMVRQYM KEEEMRAAHQ SSLLRLREKA LKEKTKAELA
WLEHQKKHLR DKGEDDKMPP IRKRQRGLLL RLQQEKAEIK RLQEANKAAR KERQLILKQQ
AEIERIRQTT MKLQEKLKSA GENKLELPSE DDIKQSNGSS PLPTDAETRS PSPISISSSE
TSSIMQKLKK MRSRMDEKFL TKREQKLMQR RQHAEELLEW KRRLDAEEAE IRRMEKQALA
AWDKELLKTK IAKKELGDQS AEPKETASEE ESPVPSCSHL NSESSIPEDL GSLAAESVPS
EPMGHGQPES PDQSTVNEEM AYSEDFKSSA SPGKLSPPKS SISVSKQDSS KGSHRTGGQL
HSPVKSHQTS HNWSDESLSM TQSETTSDQS DIEGRIRALK DELRKRKSVV YQLKKEQKKR
QKERLKAQEA SLIKQLESYD EFIKKTEAEL SQDLEASPTA KPQIKTPSSA AAEKPKIKAP
PLHRPETAKN WKSLTESERS RASLESVSEL ADAVSSRTER SVSMHTKKVA VTAVHAGEPS
GRASLASVLP KSSRAGSGDS SDSYSARPKD MKDISRISLE SVNKVVNASG VDPTISHKSE
ITEDLEYIKS EEYESGGSNV KPVESSDVLL TLDEGRESSL GPGSENRLSQ KELLDVAVES
LHDTEEIFEQ RQSNKDDVSG PSIEETSHKL SKSAEEKGDL LSEQLLSQKE PSYPEDFEGS
SSRKQAASEE TLPGEHYRDD FEGSLLSANG KSLREQSQHS QASRSRSTSL GSDGEISECL
SDRSLSGSVH SERLLELKSP TELMKNAERR DVEQEQAPAC SPLWASASIT EETDSLSNFG
IGDRVLVSKV QPGTLRFKGL TKFAKGFWAG VELDEPEGNN NGTYDDIKYF DCREKHGIFA
PPQKISHITE SIDRHLDTNK DDEDSFFDDR LEKQHKAEQK DRESSKPVKE AESQSRNTSE
NYSQDKAPVD TAVSEASAEG RVEEELSSKA NSIKEIFVAI GSFAQEQSVV NYLKDAVKEE
ASHTPLTSSI VEEVSTVQLD DVSDFLSEKL ERQKTLGEEC AEKLDDLSPG VVEKPATPLL
DLLTKEKNQL EAQLSLPLRE EEKSKDQLEK VSLLTDSLLR DFVKDTVNQL QQIKKIKNEK
IQLSNQELCD VKEEDITPPQ QVEQQIPDGL SNFFLSSDLE DDREELSSPD MCPRPESPVF
GASGQEELAK RLAELELNRE FLSVLGDDQD WFDEDYGLSS SKLQQKQSEE PAVLPQAEPQ
KVPTKPSEEP LAVPHTAVEV EGMVHAAAEQ LWKLKELGHD LQSCSLKTDL CGTLQEQDTD
TINKQVYRKV VFDLTREIFG EIFAEDPNLN QPIWMKPCRI ASAYFRRVKD PNDLDEIKNF
IAAEVLKLFS LRKEPNHKTD WQKMMKFGRK KRDRVDHILV QELHEEEAQW VNYDEDELCV
KMQLADGIFE ALIRDTVDVL NQINEKQRRL LLV
//
