ID H1ADV3_AEGBI Unreviewed; 417 AA.
AC H1ADV3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=PolA1 {ECO:0000313|EMBL:BAL46447.1};
OS Aegilops bicornis (Spach goatgrass) (Triticum bicorne).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=4483 {ECO:0000313|EMBL:BAL46447.1};
RN [1] {ECO:0000313|EMBL:BAL46447.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KU14615 {ECO:0000313|EMBL:BAL46447.1};
RA Bhuwan R., Hiroko T., Ikuo N.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAL46447.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KU14615 {ECO:0000313|EMBL:BAL46447.1};
RA Rai B., Takahashi H., Nakamura I.;
RT "Protein tag sequence of PolA1 gene in Triticum-Aegilops species.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; AB647284; BAL46447.1; -; Genomic_DNA.
DR AlphaFoldDB; H1ADV3; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.70.2850; -; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF11; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 299..415
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT REGION 122..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..218
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..359
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAL46447.1"
FT NON_TER 417
FT /evidence="ECO:0000313|EMBL:BAL46447.1"
SQ SEQUENCE 417 AA; 47091 MW; BB92664DEA322520 CRC64;
IQEILMKASA NISTPVMVCP LREDIPRDEA KRLETKLRGI RLADIVEGME VCTIPFHNSN
GHISSLYKLQ LKLFSPECYP PESELTVDEC QAALRTVFVD AMEYAIEKHV NFLHKVSGIQ
ETRVKDTESS PSDGPEESES RPIDGEESGA SDGDDENDDD LGADAEKRKR QENDEMEYDD
DIEEKDGMNS DPEEETKYEL DNEDGPAESG EESEENDEGH LSDSSNKTAK LEGRLAAGKL
KKGKKETVEN LEEQKQKQIT QKRSKKLKLT VHVESTDLKF EVHYILHKEP HILLSQIAQK
TLKSLFVSAS HNKSISECTV VWPEEKDNST KKKKGDSTTK KKKKDDSSQE EEKKNDSTNK
NKVQTSGVDF EVFWDLQDYL DIHKLTSNDI HAILNTYGVE AARATIINEV KAVFEPF
//
